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SCI Clinical Trials in Colorado

49 spinal cord injury clinical trials list a study site in Colorado, and 14 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Colorado or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in Colorado: inpatient SCI rehab facilities in Colorado · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (14)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT07024407

    A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.

    This is an open-label study of andecaliximab in participants at risk of developing bone where bone should not be, such as in muscle, tendons, and other soft tissues following traumatic spinal cord injury.

    Drugs
    1 US site · Colorado
  • Not yet recruitingNCT07799532

    A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

    The goal of this clinical trial is to learn if NVG-291 can improve function in adults with chronic cervical motor-incomplete spinal cord injury. It will also learn about the safety of NVG-291.

    DrugsSafetyBlood PressureHand MovementMotor FunctionQuality of LifeSpasticityTemperature Control
    18 US sites · Alabama, California, Colorado, Connecticut…
  • RecruitingNCT07147296

    ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

    Empower BP is a pivotal, interventional, multicenter, prospective, randomized, controlled double-blinded study to evaluate the safety and effectiveness of the ARC-IM System in managing symptomatic blood pressure instability in individuals with chronic SCI (\>1 year after SCI).

    Epidural StimulationBlood Pressure
    13 US sites · Arkansas, Colorado, Florida, Georgia…
  • RecruitingNCT06345781

    Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury

    The primary objective of this study is to gather information about the effectiveness of abdominal FES to improve bowel management time (BMT) for people with chronic SCI.

    Bowel Function
    1 US site · Colorado
  • RecruitingNCT07227727

    Endothelial Dysfunction After SCI

    This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury.

    Quality of Life
    1 US site · Colorado
  • Enrolling by invitationNCT05966896

    Epidural Stimulation to Restore Voluntary Movement Following Spinal Cord Injury

    This proof-of-concept case series will prospectively use magnetic resonance imaging (MRI) evidence of spared spinal cord neural fibers to guide the selection of 2 research participants to receive a surgically implanted epidural stimulator with the goal of restoring voluntary movement after spinal…

    Epidural Stimulation
    1 US site · Colorado
  • Enrolling by invitationNCT06906536

    Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function

    The goal of this study is to clarify mechanisms of acute intermittent hypoxia and to examine the effect on lower limb function in persons with chronic, incomplete spinal cord injury.

    Intermittent HypoxiaRehabilitationRegeneration
    1 US site · Colorado
  • Enrolling by invitationNCT05191121

    Improving Upper Extremity Function and Trunk Stability After Cervical Spinal Cord Injury (SCI)

    Ninety-nine individuals meeting the study's inclusion/exclusion criteria will be enrolled in this study. The objective of this study is to evaluate three different therapeutic approaches to synergistically retrain functional movement patterns of the upper extremities in combination with trunk…

    Hand Movement
    1 US site · Colorado
  • RecruitingNCT05491525

    Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC

    The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC

    DrugsBladder Function
    38 US sites · Arkansas, California, Colorado, Florida…
  • RecruitingNCT06443151

    Role of Endothelial Function in SCI CVD Risk

    Individuals with spinal cord injury have heart attacks and strokes more frequently, and much earlier in life. People with spinal cord injuries develop plaque in vessels much faster, and the reasons why are unclear.

    Observational
    1 US site · Colorado
  • RecruitingNCT01964261

    Sensory Motor Transformations in Human Cortex

    This research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a spinal cord injury some ability to control an external device such as a computer cursor or robotic limb by using their thoughts along with…

    Brain Stimulation
    4 US sites · California, Colorado
  • RecruitingNCT06743607

    Spinal Stimulation for Upper Extremity Recovery in the Home

    The purpose of this research is to evaluate the safety, feasibility, and tolerability of non-invasive spinal stimulation used in the home and/or community in combination with a functional home exercise program for the upper extremities (arm/hand function) as well as their combined impacts on…

    Transcutaneous StimulationArm MovementHand Movement
    1 US site · Colorado
  • RecruitingNCT07227740

    Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury

    Heart attacks and strokes are among the most common causes of premature death in individuals living with spinal cord injury (SCI) and appear to occur earlier in life.

    Quality of Life
    1 US site · Colorado
  • Not yet recruitingNCT07742553

    Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial

    Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.

    DrugsBone StrengthLeg MovementMotor FunctionQuality of LifeWalking Function
    4 US sites · Colorado, Florida, New York

Running, but closed to new participants (1)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT05982171

    Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury

    The goal of this clinical trial is to investigate the effects of transcutaneous spinal cord stimulation (TSCS) combined with exoskeleton training, as compared to exoskeleton training alone to improve motor function in individuals with incomplete spinal cord injury who are 12 months or less…

    ExoskeletonTranscutaneous Stimulation
    1 US site · Colorado

Completed and closed (34)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT00412308 A Comparison of High vs. Low Tidal Volumes in Ventilator Weaning for Individuals With Cervical Spinal Cord Injuries
  • Completed NCT02853149 A Lifestyle Intervention Targeting Enhanced Health and Function for Persons With Chronic SCI in Caregiver/Care-Receiver Relationships: Effects of Caregiver Co-Treatment
  • Unknown NCT06238492 A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI
  • Completed NCT00557973 A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury
  • Completed NCT00432289 Acupuncture for Treatment of Acute Spinal Cord Injury: an Exploratory/Developmental Study
  • Completed NCT04141891 Advancing Understanding of Transportation Options
  • Suspended NCT00073853 Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries
  • Completed NCT03975075 Biofeedback Treatment of Anxiety Associated With Chronic Spinal Cord Injury
  • Completed NCT03554733 Bridge Reinvention
  • Completed NCT04379011 Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
  • Completed NCT00318591 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections
  • Completed NCT04912583 Comparison of Low and High Tidal Volumes in Acute Spinal Cord Injury
  • Completed NCT00047580 Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
  • Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
  • Completed NCT02110290 Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities
  • Completed NCT00010374 Electrical Activation of The Diaphragm for Ventilatory Assist
  • Completed NCT02392052 Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury
  • Completed NCT06850363 ExaStim Upper Limb Home Use Clinical Validation Study
  • Completed NCT01815554 Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia
  • Completed NCT02201173 Health Outcomes After Locomotor Training in Spinal Cord Injury
  • Completed NCT02202538 Indego® Exoskeleton; Assessing Mobility for Persons With Spinal Cord Injury (SCI).
  • Completed NCT00320281 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.
  • Completed NCT05284201 LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury
  • Completed NCT04991415 Manual Therapy for the Treatment of Shoulder Pain for Overuse Syndrome Wheelchair Dependent Persons
  • Completed NCT01633164 Re-Inventing Yourself After Spinal Cord Injury
  • Unknown NCT03390140 ReInventing Yourself After SCI: an Intervention to Improve Outcomes After Spinal Cord Injury
  • Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Unknown NCT02946424 Simvastatin to Prevent SCI-Induced Bone Loss
  • Completed NCT05301335 Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
  • Terminated NCT03762655 Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
  • Completed NCT01502631 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
  • Completed NCT05341466 The Effect of Acute Intermittent Hypoxia on Motor Learning
  • Completed NCT04697472 The Up-LIFT Study of Non-Invasive ARC Therapy for Spinal Cord Injury
  • Completed NCT05068648 Wheelchair Backs That Support the Spinal Curves

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".