Devices Clinical Trials for Spinal Cord Injury

SCI.help tracks 359 spinal cord injury clinical trials studying devices, and 54 are open to new participants. Each links to its full ClinicalTrials.gov record. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

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Open and recruiting (54)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT07720882

    A Clinical Study of a Fully Implanted, Wireless and Functional BCI for Upper-Limb Functional Replacement in Tetraplegia Due to Spinal Cord Injury: Efficacy and Safety

    This prospective, multicenter, single-arm clinical trial will enroll subjects with tetraplegia secondary to spinal cord injury.

    Brain Machine Interface (BMI)DevicesArm MovementMotor Function
    China
  • RecruitingNCT06097000

    A Study of the Safety and Efficacy of Intelligent Powered Exoskeletons in Postoperative Spinal Rehabilitation

    Systematic and professional rehabilitation training is generally effective for patients with lower limb dyskinesia, but most of them lose the chance of recovery due to failure to receive systematic rehabilitation treatment.

    DevicesExoskeletonRehabilitationSurgical ProcedureLeg MovementMotor FunctionWalking Function
    China
  • RecruitingNCT06538974

    Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population

    In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990.

    DevicesExoskeletonRehabilitationBladder FunctionBowel FunctionLeg MovementMental HealthMotor FunctionQuality of Life
    France
  • Not yet recruitingNCT07396922

    Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments

    This study will evaluate the safety and performance of the Spatial StimeMD (SSMD) medical device in people with multiple sclerosis (MS). The SSMD device is intended to support patients through a non-invasive stimulation program.

    Poland
  • Not yet recruitingNCT07209943

    Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro

    The goal of this study is refine the usability of a BCI capable communication platform. The study will take place in the United States area and will enroll up to 10 participants with late stage ALS, traumatic brain injury (TBI) or spinal cord injury (SCI) that have assistive communication and…

    1 US site · California
  • RecruitingNCT04623593

    Cervical Arthroplasty Cost Effectiveness Study (CACES)

    To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD). The most commonly used surgical treatment for patients with single- or multilevel symptomatic CDDD is anterior cervical discectomy with fusion (ACDF).

    DevicesSurgical ProcedureMental HealthPain Management
    Netherlands
  • RecruitingNCT07539025

    Cervical Spinal Cord Associative Plasticity

    Associative plasticity has been used to promote functional recovery from conditions affecting movement. Prior work from the Carmel laboratory has shown that paired associative stimulation protocols timed to converge in the cervical spinal cord induce significantly larger upper limb motor responses…

    DevicesArm MovementHand MovementPlasticity
    1 US site · New York
  • RecruitingNCT07745712

    Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting

    The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program in a clinical setting.

    DevicesRehabilitationLeg MovementMental HealthMotor FunctionPain ManagementQuality of LifeSpasticity
    Spain
  • RecruitingNCT07407725

    Clinical Outcome Assessment for AT & BCI

    Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers.

    1 US site · Illinois
  • Not yet recruitingNCT07689227

    Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)

    The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in individuals with mobility impairments resulting from chronic, incomplete spinal…

    DevicesRehabilitationLeg MovementMotor FunctionPain ManagementQuality of LifeWalking Function
    4 US sites · Massachusetts, Texas
  • Not yet recruitingNCT07704268

    Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI

    This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder contractions) and related voiding dysfunctions in patients with spinal…

    DevicesTranscranial Magnetic Stimulation (TMS)Bladder FunctionQuality of LifeSensory Function
    China
  • RecruitingNCT07237386

    Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neurological Populations

    Ceriter Stride-One soles have been available on the market for several years. One of the features of these soles is that they can measure gait parameters while patients walk around in a functional environment.

    DevicesRehabilitationWalking Function
    Belgium
  • RecruitingNCT05906056

    Continuous Passive Motion Versus Heterotopic Ossification

    The investigators hypothesize that Heterotopic Ossification (HO) formation can be suppressed if the application of a Continuous Passive Motion (CPM) device can be performed for a substantial amount of time.

    Greece
  • Not yet recruitingNCT07668063

    Device for Bladder Control for Men With SCI

    Urinary incontinence, bladder frequency, and bladder urgency are significant medical problems for people with overactive bladder (OAB) or neurogenic bladder overactivity (NDO).

    1 US site · Ohio
  • RecruitingNCT04855838

    Dysphagia After Anterior Cervical Spine Surgery

    The purpose of this research project is to investigate the incidence of impaired swallowing (dysphagia) after anterior cervical spine surgery (ACSS) and to study the long-term effect of dysphagia on nutritional status 12 ± 3 months later.

    Sweden
  • Not yet recruitingNCT07653529

    Effect of Antigravity Treadmill Training on Cardiorespiratory Fitness and Lower Limb Function in Incomplete Spinal Cord Injury

    This study aims to investigate the effect of locomotor training using an antigravity treadmill on cardiorespiratory fitness and lower limb function in patients with incomplete spinal cord injury.

    DevicesRehabilitationLeg MovementTrunk ControlWalking Function
  • Enrolling by invitationNCT07732868

    Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury

    Spinal cord injury (SCI) is a highly debilitating pathology, associated with the loss of sensorimotor functions, autonomy and quality of life. Although there is currently no cure, brain-machine interfaces (BMI) have been used as a method of SCI rehabilitation.

    Brain Machine Interface (BMI)DevicesExoskeletonRehabilitationPain ManagementQuality of LifeSensory FunctionWalking Function
    Portugal
  • RecruitingNCT04906928

    Evaluation of New MRI Sequences Including 3D-FGAPSIR for the Optimization of Inflammatory Spinal Cord Lesions Research

    * verification of inclusion and non-inclusion criteria * information and collection of consent * standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), 3D STIR and 3D PSIR sequence.

    France
  • Not yet recruitingNCT07616050

    Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients

    The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions.

    Italy
  • Not yet recruitingNCT07131553

    Evaluation of the Wheelchair School (Drivkraft) a Clinical Study

    This project will evaluate the Wheelchair School with the Drivkraft Methodology in a clinical setting. Participants are adults with chronic neurological diagnoses.

    Sweden
  • RecruitingNCT05724173

    Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

    The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.

    2 US sites · California, Massachusetts
  • RecruitingNCT06094205

    Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

    The goal of this study is to improve our understanding of speech production, and to translate this into medical devices called intracortical brain-computer interfaces (iBCIs) that will enable people who have lost the ability to speak fluently to communicate via a computer just by trying to speak.

    1 US site · California
  • RecruitingNCT07429188

    Impact Study on Users of Upper Limb Assistive Devices

    This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and Human and Social Sciences (HSS), targets the use case of employing…

    DevicesArm MovementHand Movement
    France
  • RecruitingNCT07784088

    Implantable Wireless Brain-Computer Interface Systems in Patients With Tetraplegia

    Objectives of Study: This trial aims to evaluate the safety and efficacy of an implantable wireless brain-computer interface system in patients with tetraplegia resulting from spinal cord injury.

    Brain Machine Interface (BMI)DevicesMental HealthQuality of Life
    China
  • RecruitingNCT06920524

    Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)

    Botulinum toxin (BT) injections are a painful treatment frequently used to treat spasticity following central neurological damage (stroke, multiple sclerosis, spinal cord injury, head trauma). Tolerance of injections varies from patient to patient.

    DevicesRehabilitationMental HealthPain ManagementSpasticity
    France
  • RecruitingNCT05776030

    Multi-speed Ergonomic Wheelchair

    Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain.

    DevicesPain ManagementQuality of Life
    1 US site · Minnesota
  • Not yet recruitingNCT07711015

    Myofascial Release and 20-m Speed in Wheelchair Rugby Athletes With Spinal Cord Injury

    This study aims to investigate the effect of myofascial release on sprint performance in wheelchair rugby athletes with spinal cord injury.

    DevicesArm Movement
    Brazil
  • RecruitingNCT07541612

    NIRS MONITORING OF SPINAL CORD ISCHEMIA IN AORTIC SURGERY

    This prospective observational study aims to evaluate the feasibility and clinical utility of near-infrared spectroscopy (NIRS) monitoring applied to paraspinal muscles as a surrogate marker of spinal cord perfusion in patients undergoing major noncardiac surgery.

    Italy
  • Not yet recruitingNCT06831240

    New Rear Anti-tip Device for Manual Wheelchairs: Subjective Input (RAD-SI)

    The objective of this study is to obtain subjective input from wheelchair service providers and end-users about their experiences with conventional rear anti-tip devices (C-RADs) of manual wheelchairs and the potential usefulness of a new design.

    Canada
  • RecruitingNCT07674927

    Pilot Study Exploring the Effects of Rhythmic Auditory Stimulation on Gait in People With Motor Incomplete Spinal Cord Injury

    This pilot study aims to evaluate the feasibility and preliminary efficacy of a wearable rhythmic auditory stimulation system, MedRhythms, for improving gait parameters in patients with motor incomplete SCI. Up to 15 participants aged 18 years or older with non-progressive SCI will be enrolled.

    DevicesRehabilitationQuality of LifeWalking Function
    1 US site · California
  • Not yet recruitingNCT07527728

    Postoperative Neurological Recovery and Risk Factor Analysis in Patients With Paralysis Due to Spinal Metastases

    Metastatic spinal tumors represent a common and devastating complication in patients with advanced solid malignancies. Up to 40% of cancer patients may develop spinal metastases during the course of their disease, often resulting in intractable pain, neurological deficits, and spinal instability.

    DevicesDrugsEpidural StimulationObservationalSurgical ProcedureBladder FunctionBowel FunctionMotor FunctionPain ManagementQuality of LifeSpasticity
  • Not yet recruitingNCT07798310

    Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury III (PROMPT-SCI III) Trial

    This longitudinal cohort study will investigate the clinical benefits of early acute exercise therapy after mild spinal cord injury (SCI).

    DevicesSurgical ProcedureMotor FunctionPain ManagementQuality of LifeWalking Function
    Canada
  • Not yet recruitingNCT07639541

    Radio-frequency (RF) Bladder Monitor

    The goal of this pilot feasibility study is to evaluate a wearable microwave (MW)-based bladder monitoring system in adult volunteers and those with spinal cord injury (SCI) who use self-catheterization for bladder management.

    DevicesBladder Function
    Canada
  • RecruitingNCT07280923

    Reliability and Validity of the PReFS

    This study is testing the psychometric properties of a new tool to determine recommendations for pressure relief frequency in wheelchair users.

    DevicesPressure Sores
    1 US site · Texas
  • RecruitingNCT07404761

    Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments

    This is a multicenter, randomized, controlled clinical study evaluating the safety and effectiveness of the Spatial StimelMD (SSMD) device for upper-limb neuromotor rehabilitation in adults with impairment following stroke or traumatic brain injury (TBI).

    Israel
  • Not yet recruitingNCT07159360

    Safety, Usability, and Effectiveness of a Gait Exoskeleton for Children and Adolescents With Neurodevelopmental Disorders.

    Neurodevelopmental disorders often result in abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as the inability to stand and walk.

    DevicesExoskeletonRehabilitationBlood PressurePain ManagementQuality of LifeSpasticityWalking Function
    Mexico, Spain
  • RecruitingNCT07501429

    Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury

    Approximately 305,000 people live with a spinal cord injury (SCI) in the United States. Sixty percent of these individuals have tetraplegia, which can cause significant dysfunction of the arms and hands.

    DevicesSpasticity
    1 US site · New Jersey
  • RecruitingNCT07245706

    Shoulder Health After Rehabilitation and Performance Training

    The goal of this study is to investigate the impact of a home-based shoulder strength training on the overall shoulder health in manual wheelchair users, and if the timepoint of such a training makes a difference.

    DevicesQuality of Life
    Switzerland
  • RecruitingNCT07153536

    Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

    This study plans to use systems that have been developed by Medtronic to investigate the use of cervical spinal cord stimulation to treat adults with upper limb hemiparesis resulting from a stroke.

    DevicesElectrical StimulationRehabilitationArm MovementMotor FunctionSpasticity
    1 US site · Pennsylvania
  • Not yet recruitingNCT07785258

    TTNS in SCI Patients With Neurogenic Detrusor Overactivity

    This is a prospective, single-arm, pilot study to assess effectiveness and tolerability of transcutaneous tibial nerve stimulation (TTNS) in managing neurogenic detrusor overactivity in spinal cord injury patients.

    Singapore
  • RecruitingNCT06349434

    The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI

    To evaluate the usefulness of an upper extremity assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury. The Department of Defense is supporting this study.

    DevicesArm MovementMotor FunctionSpasticity
    1 US site · New Jersey
  • RecruitingNCT07136688

    Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

    The purpose of this study is to determine the safety, feasibility, and compliance of a daily home transcutaneous tibial nerve stimulation (tTNS) protocol in children with chronic neurogenic bladder (NB) provided by self or caregiver for 4 weeks and to estimate the efficacy of tTNS

    DevicesTranscutaneous StimulationBladder FunctionBowel FunctionMental HealthSensory Function
    1 US site · Texas
  • RecruitingNCT06998134

    Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

    People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs. The NIH designed a new brace device, called an exoskeleton, that is worn on the legs and helps people walk.

    1 US site · Maryland
  • Not yet recruitingNCT07745686

    VALSE: Integration of Neuromodulation and Exoskeleton Systems for Mobility in Individuals With Chronic Spinal Cord Injury

    The purpose of this clinical study is to evaluate the preliminary safety and feasibility of using the VALSE system, which combines spinal cord stimulation with the TWIICE robotic exoskeleton, to support motor recovery and reduce reliance on laboratory-based equipment during rehabilitation in…

    Switzerland
  • RecruitingNCT07224256

    VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

    The VOICE Study is an early feasibility study to evaluate the initial clinical safety and efficacy of the N1 and R1 Systems device design concept in providing an ability to communicate.

    1 US site · Texas
  • RecruitingNCT06295146

    Virtual Peer Coaching in Manual Wheelchair Skills

    The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained.

    1 US site · Pennsylvania
  • RecruitingNCT07750808

    ZEPU AI9 Exoskeleton Rehabilitation Robot

    The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic surgery.

    DevicesExoskeletonRehabilitationSurgical ProcedureLeg MovementMotor FunctionPain ManagementQuality of LifeSpasticityTrunk Control
    Bangladesh
  • RecruitingNCT07749612

    ZEPU-2000 Limb Rehabilitation Trainer Study (ZEPU2000RCT)

    The goal of this clinical trial is to learn whether the ZEPU-2000A, ZEPU-2000D and ZEPU-2000E robotic rehabilitation trainers help people with weakness or movement problems in their arms and legs. These devices are used to guide repeated arm and leg movements as part of rehabilitation therapy.

    DevicesRehabilitationArm MovementLeg MovementMotor FunctionQuality of LifeSpasticityTrunk Control
    Bangladesh
  • RecruitingNCT07749625

    ZEPU-AI Series Limb Feedback Robot Training Study (ZEPUAISRCT)

    The goal of this clinical trial is to learn whether robotic rehabilitation devices (ZEPU-AI2, AI4, AI6 Plus, and AI7A) are feasible, safe, and effective for adults with upper or lower limb motor problems.

    DevicesRehabilitationSurgical ProcedureArm MovementHand MovementLeg MovementMotor FunctionPain ManagementQuality of Life
    Bangladesh
  • RecruitingNCT07735676

    ZEPU-AI1 Gait Robot Training Study (ZEPUAI1RCT)

    Walking problems caused by stroke, spinal cord injury, or orthopedic surgery are common and can seriously limit a person's independence.

    DevicesExoskeletonRehabilitationSurgical ProcedureLeg MovementMotor FunctionQuality of LifeSpasticityTrunk ControlWalking Function
    Bangladesh
  • RecruitingNCT07705906

    ZEPU-AI3 Lower Limb Feedback Robot Training Study

    Lower limb motor dysfunction resulting from stroke, spinal cord injury, or other neurological disorders substantially limits mobility, independence, and quality of life. Robotic rehabilitation has emerged as a promising approach to provide intensive, repetitive, task-oriented training.

    DevicesRehabilitationLeg MovementMotor FunctionQuality of LifeSpasticityTrunk ControlWalking Function
    Bangladesh
  • RecruitingNCT07735702

    ZEPU-AI5 Strength Training Study (ZEPUAI5RCT)

    The goal of this clinical trial is to learn if robot-assisted lower-limb strength and gait training can improve safety, feasibility, and functional recovery in adults aged 18-60 years with lower-limb motor dysfunction due to stroke, incomplete spinal cord injury, or persistent gait impairment…

    DevicesRehabilitationSurgical ProcedureLeg MovementMotor FunctionQuality of LifeSpasticityTrunk ControlWalking Function
    Bangladesh
  • RecruitingNCT07739264

    ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)

    The goal of this pilot randomized controlled trial is to learn whether the ZEPU-SG1PLUS Hand Functional Comprehensive Training System - a robotic device used alongside standard rehabilitation - is safe, feasible, and helpful for people with upper limb (arm/hand) motor problems caused by stroke,…

    DevicesRehabilitationArm MovementHand MovementMotor FunctionQuality of LifeSpasticity
    Bangladesh
  • Not yet recruitingNCT05470478

    iBCI Optimization for Veterans With Paralysis

    VA research has been advancing a high-performance brain-computer interface (BCI) to improve independence for Veterans and others living with tetraplegia or the inability to speak resulting from amyotrophic lateral sclerosis, spinal cord injury or stoke.

    1 US site · Rhode Island

Running, but closed to new participants (5)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT06765070

    Efficacy and Usability of the EXPLORER Exoskeleton in Children With Neurodevelopmental Disorders in Natural Environments

    Neurodevelopmental disorders often lead to abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as an inability to stand and walk.

    DevicesExoskeletonPain ManagementQuality of LifeWalking Function
    Spain
  • Active, not recruitingNCT07669181

    Examination of the Role of Human Exoskeletons in Rehabilitation

    Background and Rationale: Traumatic spinal cord injury (SCI) affects approximately 12,400 individuals annually in the USA, predominantly impacting healthy young adults aged 20-40 years. Complete SCI above the lumbar region results in paraplegia or tetraplegia, severely compromising quality of life.

    DevicesExoskeletonRehabilitationBone StrengthBowel FunctionLeg MovementMental HealthMotor FunctionPain Management
    Hungary
  • Active, not recruitingNCT06872931

    Investigation of the Effects of C-Mill (Hocoma AG, Switzerland) Treadmill Training on Trunk Balance in Patients with Spinal Cord Injury

    This study examines how C-Mill treadmill training affects balance and stability in people with spinal cord injury (SCI). Many individuals with SCI experience difficulty with sitting and walking balance, which affects their daily activities and independence.

    DevicesRehabilitationQuality of LifeTrunk Control
    Turkey (Türkiye)
  • Active, not recruitingNCT04248322

    Qualitative Assessment of the Impact of TTNS on QOL and Participation

    This study through the use of semi-structured interviews or focus groups will explore the lived experience with Transcutaneous Tibial Nerve Stimulation (TTNS) with Neurogenic Lower Urinary Tract Dysfunction to generate user-defined themes regarding bladder function and catheter-related barriers and…

    DevicesObservationalTranscutaneous StimulationBladder FunctionQuality of Life
    1 US site · District of Columbia
  • Active, not recruitingNCT05593237

    Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

    Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat. Current available treatments have low efficacy, high side effect burden, and are prone to misuse and dependence.

    1 US site · California

Completed and closed (300)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT02025179 12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
  • Completed NCT00345397 A Colonic Tube to Improve Bowel Function in Spinal Cord Injury
  • Completed NCT01923662 A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
  • Completed NCT05441449 A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
  • Completed NCT00990093 A Randomised, Cross-over, Open-labelled Test Catheter Acceptance Study
  • Completed NCT04977037 A Telerehabilitation Program for SCI
  • Completed NCT06087445 A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia
  • Completed NCT02803255 AAN Robotic Therapy in SCI
  • Withdrawn NCT02970773 Absorption of Rivaroxaban in Patients With Cervical Spinal Cord Injury
  • Completed NCT06159946 Access-H20 Faucet for Spinal Cord Injury
  • Completed NCT07062796 Access-H20: Sensor-driven Smart Faucet
  • Completed NCT07603258 Access-H20: Sensor-driven Smart Faucet Related Study
  • Completed NCT02307526 Acetylcholinesterase Inhibition and Orthostatic Hypotension in SCI
  • Completed NCT03696927 Active Powered Prosthesis (APEX) for Spinal Cord Injury
  • Completed NCT04247828 Adaptive and Individualized AAC
  • Completed NCT05740527 Ambulatory Closed-loop Stimulation for Bladder Control
  • Completed NCT04340063 Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
  • Terminated NCT01112774 Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury
  • Terminated NCT02778529 Arm Motor Control on Bi and Uni ADLs
  • Completed NCT02098135 ArmeoSenso - Home Therapy and Assessment for Patients With Arm Impairments Based on Wearable Movement Sensors
  • Terminated NCT03664479 Assess the Safety and Efficacy of the 4 Channel NMES, Pilot Study
  • Completed NCT02562001 Association Between tDCS and Lokomat Training in Patients With Incomplete Spinal Cord Injury
  • Completed NCT04309448 Augmenting Reactive Stepping With FES After SCI
  • Completed NCT06588608 Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)
  • Withdrawn NCT06661057 Avation Electric Stimulation System for Spinal Cord Injury Neurogenic Bladder
  • Completed NCT00645567 Biomechanics of Wheelchair Transfers
  • Completed NCT02703883 Body Weight Support in Spinal Cord Injury
  • Completed NCT03307954 Bone Mineral Density Ekso Therapy Study
  • Unknown NCT06161168 Bootle Blast: Understanding the Family Experience
  • Completed NCT02564419 Brain Machine Interface (BMI) in Subjects Living With Quadriplegia
  • Completed NCT02678494 Brain-Train Home Based Pain Treatment
  • Completed NCT02443558 Brainwave Control of a Wearable Robotic Arm for Rehabilitation and Neurophysiological Study in Cervical Spine Injury
  • Unknown NCT03567902 C-MAC Videolaryngoscope Intubation and Cervical Spine Motion
  • Completed NCT05530798 CEUS For Intraoperative Spinal Cord Injury
  • Completed NCT04309864 CMAP Refinement for Pressure Injury Prevention
  • Completed NCT01935687 Clinical Evaluation of Instrumented Wheel as Biomedical Device Quantifying the Displacement Efficiency
  • Completed NCT00011609 Clinical Evaluation of a Wheelchair Mounted Robotic Arm
  • Completed NCT05643313 Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments
  • Completed NCT04876794 Clinical Investigation on Safety, Feasibility and Usability of the ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting
  • Completed NCT05590065 Clinical Investigation on the Impact on Safety, Feasibility and Usability of the Design Changes Performed on ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting
  • Withdrawn NCT01292941 Clinical Study Evaluating Safety of a New Catheter for Urinary Intermittent Catheter in Healthy Volunteers
  • Completed NCT04304976 Clinical Trial ROBERT® - Project Active Training
  • Unknown NCT05883917 Clinical Utility of Robot-Assisted Gait Training in Patients With Spinal Cord Injury Caused by Electrical Burns: A Case Report
  • Completed NCT03029884 Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
  • Completed NCT04577573 Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI
  • Completed NCT02554058 Combined Tactile and Proprioception Training After Spinal Cord Injury
  • Completed NCT00318591 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections
  • Completed NCT01407354 Comparison of Lokomat and Aquatic Exercise for Individuals With Chronic Incomplete Spinal Cord Injury
  • Completed NCT04912583 Comparison of Low and High Tidal Volumes in Acute Spinal Cord Injury
  • Completed NCT04360447 Comparison of Pilates &Home Exercise Programs on Muscle Strength in Paraplegic Patients
  • Completed NCT02244931 Comparison of Three Different Assisting Devices to Power Manual Wheelchairs in Patients With Spinal Cord Injury
  • Completed NCT05071885 Computer Game-based Exercise Program Targeting Manual Dexterity for People With Spinal Cord Injury or Stroke.
  • Completed NCT03626324 Connected Catheter (C2P) Study for Bladder Management
  • Terminated NCT04059159 Connected Catheter - Safety and Effectiveness Study
  • Completed NCT03405285 Connected Catheter Clinical Feasibility Study( CFS)
  • Terminated NCT03843073 Connected Catheter- Safety and Effectiveness Study
  • Terminated NCT03114345 Correlation Between Pressure Differences and Micro-vascularization Changes in Bedridden Paraplegic Patient
  • Completed NCT06445426 Cystometry Using a Novel Microsensor System in Patients With Neurogenic Bladder Dysfunction
  • Withdrawn NCT04325165 DBS of PPN to Improve Walking in Chronic SCI Patients
  • Completed NCT02336321 Daily-life Brain Control Of A Hand Exoskeleton After Cervical Spinal Cord Injury
  • Completed NCT01932905 Deep rTMS in Central Neuropathic Pain Syndromes
  • Completed NCT00624806 Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
  • Completed NCT02560506 Development of Low Cost Devices to Increase Access to Treadmill Training
  • Completed NCT00392860 Development of an Ergonomic Wheelchair Pushrim
  • Completed NCT05491837 Device-induced Intermittent Hypoxia in Persons With Incomplete Spinal Cord Injury
  • Completed NCT02556125 Diaphragm Pacing After Spinal Cord Injury
  • Completed NCT04179799 Diaphragm Pacing in Individuals With Spinal Cord Injuries
  • Completed NCT01385384 Diaphragmatic Pacemaker in Tetraplegic Patients With Spinal Cord Injuries
  • Completed NCT02942953 Diaphragmatic Pacer Placement: Anesthetic Management (DP)
  • Completed NCT02630524 Diet Composition and Cardiometabolic Risk Reduction in Adults With SCI
  • Completed NCT07467850 Dual Stimulation for Spinal Cord Injury
  • Completed NCT00458471 E. Coli for Prevention of Catheter UTI in SCI Patients
  • Completed NCT01393444 ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis
  • Completed NCT03611803 EFFECTS OF ROBOTIC TRAINING ON VASCULAR HEALTH OF INDIVIDUALS WITH SCI
  • Completed NCT02268266 ERIGO® Life- Control of Cardiovascular Parameters Via Verticalization and Simultaneous Mobilization
  • Terminated NCT04319679 ESWT for UE Pain in Patients With Cervical Spinal Cord Injury
  • Completed NCT01086930 Early Intensive Hand Rehabilitation After Spinal Cord Injury
  • Completed NCT06214546 Effect of Different Support Systems on Gait
  • Completed NCT01225055 Effect of Teriparatide, Vibration and the Combination on Bone Mass and Bone Architecture in Chronic Spinal Cord Injury
  • Completed NCT02998021 Effect of Vibration Exercise on Upper Limb Strength, Function, and Pain
  • Completed NCT00886145 Effect of Vibration Therapy on Bone in Persons With Sub-acute Spinal Cord Injury
  • Completed NCT04383873 Effectiveness Analysis of Armeo Spring Device as a Rehabilitation Treatment in Spinal Cord Injured Patients
  • Completed NCT01147185 Effectiveness of Automated Locomotor Training in Patients With Acute Incomplete Spinal Cord Injury: A Multicenter Trial
  • Unknown NCT00256672 Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury
  • Unknown NCT03048357 Effectiveness of Freedom Bed Compared to Manual Turning in Prevention of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and/or Spinal Cord Injury.
  • Withdrawn NCT03533400 Effectiveness of Jamboxx Respiratory Therapy Device: Study 1
  • Completed NCT00150683 Effectiveness of Vibration and Standing Versus Standing Alone for the Treatment of Osteoporosis for People With Spinal Cord Injury.
  • Unknown NCT03118960 Effectiveness of the Freedom Bed as Compared to Alternating Pressure Mattress in Treatment of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and /or Spinal Cord Injury
  • Completed NCT02973438 Effects of Intermittent Hypoxia (IH) on Metabolism and Dysglycemia, in Overweight/Obese Persons SCI
  • Completed NCT00154505 Effects of Lateral Trunk Support on Spinal Alignment in Spinal Cord Injured Persons
  • Completed NCT05535400 Effects of Physical-Psychological Integrative Intervention on SCI Patient: a Pilot Randomized Controlled Trial
  • Completed NCT02342080 Effects of System Suspended Robotic Lokomat Gait in Patients With Incomplete Spinal Cord Injury
  • Terminated NCT04586777 Effects of Transvertebral Direct Current Stimulation in Humans
  • Completed NCT06444672 Effects of a Home-Based Rehabilitation on Anthropometric Measures, Sensory-Motor Functions and Independence After Spinal Cord Injury
  • Completed NCT04910412 Effects of tDCS With Gait Training on Leg Performance in Incomplete Spinal Cord Injury
  • Completed NCT04241003 Effects of the SmartDrive on Mobility, Activity and Shoulder Pain Among People With SCI Using Manual Wheelchairs
  • Terminated NCT01803919 Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients
  • Completed NCT02473614 Efficacy Study of the Music Glove Patients With Spinal Cord Injuries
  • Terminated NCT02198833 Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection
  • Completed NCT00010374 Electrical Activation of The Diaphragm for Ventilatory Assist
  • Completed NCT06137443 Enhancing Balance and Mobility in Incomplete Spinal Cord Injury
  • Completed NCT07717606 Epidural Stimulation and Rehabilitation for Spinal Cord Injury
  • Completed NCT01961557 Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
  • Completed NCT05744271 Evaluation of FES+VFBT With Individuals With Lived Experience
  • Completed NCT02506712 Evaluation of Physiological and Biomechanical Efficiency of the PAPAW
  • Completed NCT04523636 Evaluation of Splinting in Tetraplegia
  • Completed NCT06939634 Evaluation of Usability and Safety of the System Atalante in Patients With High Paraplegia and Tetraplegia
  • Completed NCT04323449 Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators
  • Unknown NCT03171207 Evaluation of a Novel Gait Training Device to Support Body Weight
  • Completed NCT01124292 Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis
  • Completed NCT06850363 ExaStim Upper Limb Home Use Clinical Validation Study
  • Completed NCT04221373 Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation
  • Completed NCT07352085 Exoskeleton-assisted Neurorehabilitation
  • Completed NCT04013997 Exoskeleton-assisted Walking in SCI Inpatient Rehabilitation
  • Completed NCT04083794 Exploration of Blood Flow Regulation to Bone in Humans
  • Completed NCT03337048 Exploratory Study Investigating Urodynamic Parameters During Catheterisation
  • Completed NCT02203994 Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury
  • Completed NCT05432999 Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury
  • Unknown NCT01943656 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study
  • Completed NCT00882843 Feasibility Study for the Use of Low-magnitude, High Frequency Mechanical Stimulation of Bone in Persons With Spinal Cord Injury (SCI)
  • Completed NCT02144558 Fertility of Spinal Cord Injured Men
  • Completed NCT01815554 Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia
  • Completed NCT00589199 Functional Electrical Stimulation for Production of Artificial Cough
  • Completed NCT00011557 Functional Magnetic Micturition in Patients w/SCI
  • Withdrawn NCT04847609 GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter Disorders
  • Completed NCT05470751 GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
  • Terminated NCT03447509 Grasping Function After Spinal Cord Injury
  • Terminated NCT05403606 Guarantee Assessment in Skin Prevention Adapted to Real Life With a Connected Device After a Spinal Cord Injury.
  • Withdrawn NCT01273428 HP011-101, HP828-101, and Standard Care for Pressure Ulcers
  • Completed NCT00890916 Hand Function for Tetraplegia
  • Completed NCT05128994 Hand Grasp Function After Spinal Cord Injury
  • Completed NCT05380661 Heart Rate Variability and Anxiety During Urinary Bladder Catheterization
  • Completed NCT03662308 Heated Vest for Persons With Spinal Cord Injury
  • Completed NCT04075812 High Definition Neuromuscular Stimulation in Tetraplegia
  • Completed NCT05214378 High Frequency SARS for Neurogenic Bladder and Bowel Emptying
  • Completed NCT01882257 Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
  • Completed NCT04700033 Immersive Virtual Reality for Chronic Neuropathic Pain After Spinal Cord Injury: A Feasibility Trial
  • Completed NCT03567239 Impact of Custom Assistive and Adaptive Technology in Rehabilitation
  • Completed NCT00281463 Impact of Pushrim Activated Power Assist Wheelchairs on Mobility Among People With Tetraplegia
  • Completed NCT01915095 Improving Motor Function After Spinal Cord Injury
  • Completed NCT03892746 Improving SCI Rehabilitation Interventions by Retraining the Brain
  • Completed NCT02793635 Indego Exoskeleton After SCI
  • Completed NCT02202538 Indego® Exoskeleton; Assessing Mobility for Persons With Spinal Cord Injury (SCI).
  • Completed NCT04020770 Influence of Upper Extremity Vibration on Spasticity and Function in Persons With Tetraplegia
  • Withdrawn NCT04008160 Intelligent Underwear (IU) in Paraplegics
  • Completed NCT02149186 Interactive Motor Imagery in Virtual Reality
  • Terminated NCT02230540 Intermittent Catheterization in Spinal Cord Injured Men
  • Completed NCT03071393 Intermittent Hypoxia to Enhance Motor Function After Spinal Cord Injury
  • Terminated NCT00476866 Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
  • Completed NCT06248476 Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
  • Completed NCT02168465 Internet Self-Management for People With Intermittent Urinary Catheters
  • Completed NCT02903823 Intrathecal (IT) Baclofen Drug Distribution
  • Completed NCT03945110 Intravesical Glycosaminoglycan Instillation and Urinary Tract Infection in Acute Spinal Cord Injury
  • Completed NCT04373512 Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury
  • Completed NCT03854214 Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
  • Terminated NCT02566850 Investigational Study of the Ekso for High-Dosage Use by Individuals With SCI in a Non-Clinical Environment
  • Completed NCT04855916 KAFO Orthoses Versus the ABLE Exoskeleton
  • Completed NCT03458169 LEAP a New Overground Body Weight Support Robot: Usability Trial
  • Completed NCT02600013 Locomotor Training With Exoskeleton EKSO-GT in Patients With Incomplete Motor Spinal Cord Injury in a Hospital Setting
  • Completed NCT01087918 Lokomat Versus Strength Training in Chronic Incomplete Spinal Cord Injury
  • Withdrawn NCT05226676 Long-term Effects of Repetitive TMS in Chronic Neuropathic Pain in People With SCI
  • Completed NCT03045744 Long-term PAS in Rehabilitation After SCI
  • Completed NCT03104803 Long-term Paired Associative Stimulation as a Treatment for Incomplete Spinal Cord Injury of Non-traumatic Origin
  • Completed NCT01943201 Low Friction Bed Sheet
  • Completed NCT07128901 Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury
  • Completed NCT03111277 MR Guided Focused Ultrasound for Treatment of Neuropathic Pain
  • Completed NCT01117090 Measuring Signatures in the Fluid Surrounding the Spinal Cord in Patients Who Have Problems With Intrathecal Drug Delivery
  • Unknown NCT02333695 Medical Device for Magnetic Therapy for Spinal Cord Injuries (SCI)
  • Completed NCT00221767 Medico-economical Impact of the Brindley Neurosurgical Technique in France
  • Terminated NCT02034461 Micro-Electrodes Implanted in a Human Nerve
  • Terminated NCT01364480 Microelectrode Brain-Machine Interface for Individuals With Tetraplegia
  • Completed NCT04668326 Mobile Manual Standing Wheelchair for SCI
  • Withdrawn NCT04149769 Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Home and Community Setting (SC140121 Study 3)
  • Terminated NCT04581525 Modulating Neuropathic Pain With Transcranial Direct Current Stimulation
  • Unknown NCT05032378 Motion Sensor and Feedback System Efficacy to Refine Movements After Injury
  • Completed NCT00732238 Multifaceted Treatment of Catheter-related Urinary Tract Infection
  • Completed NCT01740128 Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
  • Completed NCT05605912 Myosuit in Incomplete Spinal Cord Injury
  • Unknown NCT03632005 Negative Pressure Wound Therapy vs. Sterile Dressing for Patients Undergoing Thoracolumbar Spine Surgery
  • Completed NCT00055588 Nervous System Function in Normal Volunteers During Cycling Training
  • Completed NCT02711319 Non-invasive Brain Stimulation for Gait Improvement in Patients With Spinal Cord Injury
  • Terminated NCT02538809 Novel mRNA-based Urine Test for Bladder Cancer in Spinal Cord Injury Individuals
  • Completed NCT00860951 P300 Brain Computer Interface Keyboard to Operate Assistive Technology
  • Completed NCT03459885 PAS for Lower Extremity Rehabilitation in Tetraplegic Patients
  • Completed NCT05362422 PAS for Post-SCI Neuropathic Pain
  • Completed NCT04101916 PAS in Subacute SCI
  • Completed NCT07810712 PNS Motor Stimulation Study
  • Completed NCT05757830 PURO - PUlmonary Rehabilitation With O-RAGT Platform
  • Completed NCT00594178 Palliative Strategies in Spinal Cord Injury (SCI)
  • Completed NCT02616081 Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
  • Completed NCT07139652 Patient and Clinician Perceptions of Safe Ambulation in Incomplete Spinal Cord Injury
  • Suspended NCT05811884 Patient-centered Assessment of the Effects of Powered Exoskeleton Use in People With Spinal Cord Injury
  • Completed NCT06531304 Patient-therapist INTERaction During RObotic GAIT Rehabilitation After Spinal Cord Injury
  • Completed NCT04707144 Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T
  • Completed NCT04027972 Pharmacokinetics of Neostigmine and Glycopyrrolate
  • Completed NCT03175055 Phoenix Exoskeleton for SCI Users
  • Terminated NCT02974673 Pilot Study of Ejaculatory Dyssynergia by Electronic Microsensors of Sphincters
  • Withdrawn NCT03105882 Pilot Study of the Neuro-Spinal Scaffold for the Treatment of AIS A Cervical Acute SCI
  • Completed NCT01834417 Preliminary Study Leading to Prevention of Pressure Ulcers by the Use of an On-board Device : Ergonomic Assessment of Wheelchair-seat Pressures in Spinal Cord Injured (SCI) Patients ( PRESDIE)
  • Terminated NCT01974635 Proprioception Testing in Persons With Sensorimotor Impairment

Showing 200 of 300 closed studies. The rest are in the Trials Finder and on the state pages below.


Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".