SCI.help › Clinical Trials Finder › Stem Cells

Stem Cells Clinical Trials for Spinal Cord Injury

SCI.help tracks 52 spinal cord injury clinical trials studying stem cells, and 5 are open to new participants. Each links to its full ClinicalTrials.gov record. Last refreshed 2026-09-12.

⚠️
This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Add a target (walking, bladder, pain…), a state, or a status filter.

Other treatment categories

Browse by state

Open and recruiting (5)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • Not yet recruitingNCT06974968

    Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial

    Purpose: This clinical trial is studying an investigational cell therapy called XS228-a lab-made stem cell product designed to help repair damaged nerves in the spinal cord.

    SafetyStem CellsBladder FunctionBowel FunctionMotor FunctionQuality of LifeSensory Function
    China
  • Not yet recruitingNCT07739043

    NeuroRise: Intrathecal CE-1 Treatment for Traumatic SCI

    The purpose of this study is to assess the safety and tolerability of intrathecal administration of CE-1 at a weight-based dose (cells/kg BW), capped at a maximum total dose of 1×10⁸ cells in 10 mL, with administered volume calculated using M = 0.167 mL/kg BW.

    DrugsSafetyStem Cells
    1 US site · Illinois
  • Not yet recruitingNCT07596563

    Olfactory Cell Transplantation and Intensive Rehabilitation to Repair Chronic Spinal Cord Injury

    This is a randomised, blinded and controlled Phase I trial to measure the safety, feasibility and efficacy of a combined cell transplantation and intensive rehabilitation intervention to treat spinal cord injury.

    RehabilitationStem Cells
  • RecruitingNCT05152290

    Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for SCI

    This trial will study the safety and efficacy of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Spinal Cord Injury.

    Stem Cells
    Antigua and Barbuda, Greece
  • RecruitingNCT05018793

    Safety of Cultured Autologous Adult Adipose Derived Mesenchymal Stem Cell Versus Cultured Allogeneic Adult Umbilical-cord Derived Mesenchymal Stem Cell Intrathecal Injection for SCI

    This trial will study the safety and efficacy of intrathecal injection of cultured autologous adult adipose derived mesenchymal stem cells versus cultured allogeneic adult umbilical-cord derived mesenchymal stem cells for the treatment of spinal cord injury

    DrugsStem Cells
    Antigua and Barbuda, Greece

Running, but closed to new participants (2)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT07295067

    Extracellular Vesicles for the Treatment of Syringomyelia

    This is a open-label, single-arm, dose escalation phase I clinical trial. The goal of this clinical trial is to evaluate the safety and preliminary efficacy of Intrathecal injection human umbilical cord-derived mesenchymal stromal cell-derived extracellular vesicle (hUC-MSC-sEV) in syringomyelia.

    DrugsSafetyStem CellsBreathing Function
    China
  • Active, not recruitingNCT05975424

    LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1

    This is a LTFU study for cervical SCI subjects that were administered AST-OPC1 cells in the main study AST-OPC1-01.

    ObservationalStem Cells
    6 US sites · California, Georgia, Illinois, Pennsylvania…

Completed and closed (45)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT03308565 Adipose Stem Cells for Traumatic Spinal Cord Injury
  • Completed NCT02570932 Administration of Expanded Autologous Adult Bone Marrow Mesenchymal Cells in Established Chronic Spinal Cord Injuries
  • Completed NCT01274975 Autologous Adipose Derived MSCs Transplantation in Patient With Spinal Cord Injury.
  • Completed NCT02260713 Autologous Bone Marrow Cell Transplantation in Persons With Acute Spinal Cord Injury- An Indian Pilot Study.
  • Completed NCT01325103 Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury
  • Completed NCT02482194 Autologous Mesenchymal Stem Cells Transplantation for Spinal Cord Injury- A Phase I Clinical Study
  • Unknown NCT01694927 Autologous Mesenchymal Stem Cells in Spinal Cord Injury (SCI) Patients
  • Terminated NCT01328860 Autologous Stem Cells for Spinal Cord Injury (SCI) in Children
  • Unknown NCT02118740 Bone Marrow Collection in Healthy Volunteers (iCell)
  • Completed NCT05054803 Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury
  • Completed NCT00816803 Cell Transplant in Spinal Cord Injury Patients
  • Unknown NCT02870426 Collection and Characterisation of Human Olfactory Ensheathing Cells
  • Unknown NCT01393977 Difference Between Rehabilitation Therapy and Stem Cells Transplantation in Patients With Spinal Cord Injury in China
  • Completed NCT01873547 Different Efficacy Between Rehabilitation Therapy and Stem Cells Transplantation in Patients With SCI in China
  • Completed NCT06169969 Effect Of Magnetic Therapy In Bladder Dysfunction And Quality Of Life In Paraplegic Patients
  • Completed NCT03643770 Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury
  • Completed NCT02152657 Evaluation of Autologous Mesenchymal Stem Cell Transplantation in Chronic Spinal Cord Injury: a Pilot Study
  • No longer available NCT04064957 Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for Spinal Cord Injury
  • No longer available NCT03925649 Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for Treatment of SCI
  • Completed NCT03003364 Intrathecal Administration of Expanded Wharton's Jelly Mesenchymal Stem Cells in Chronic Traumatic Spinal Cord Injury
  • Completed NCT01624779 Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury
  • Completed NCT01471613 Lithium, Cord Blood Cells and the Combination in the Treatment of Acute & Sub-acute Spinal Cord Injury
  • Unknown NCT01446640 Mesenchymal Stem Cells Transplantation to Patients With Spinal Cord Injury
  • Completed NCT02481440 Repeated Subarachnoid Administrations of hUC-MSCs in Treating SCI
  • Completed NCT01909154 Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia
  • Completed NCT01769872 Safety and Effect of Adipose Tissue Derived Mesenchymal Stem Cell Implantation in Patients With Spinal Cord Injury
  • Completed NCT02981576 Safety and Effectiveness of BM-MSC vs AT-MSC in the Treatment of SCI Patients.
  • Completed NCT01186679 Safety and Efficacy of Autologous Bone Marrow Stem Cells in Treating Spinal Cord Injury
  • Terminated NCT01676441 Safety and Efficacy of Autologous Mesenchymal Stem Cells in Chronic Spinal Cord Injury
  • Withdrawn NCT02027246 Safety and Efficacy of Stem Cell Therapy in Spinal Cord Injury
  • Withdrawn NCT02237547 Safety and Feasibility Study of Cell Therapy in Treatment of Spinal Cord Injury
  • Completed NCT01046786 Safety and Feasibility of Umbilical Cord Blood Cell Transplant Into Injured Spinal Cord
  • Unknown NCT03225625 Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study
  • Withdrawn NCT02009124 Stem Cell Therapy in Spinal Cord Injury
  • Terminated NCT02163876 Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury
  • Unknown NCT01833975 Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Spinal Cord Injury
  • Completed NCT02165904 Subarachnoid Administrations of Adults Autologous Mesenchymal Stromal Cells in SCI
  • Completed NCT02354625 The Safety of ahSC in Chronic SCI With Rehabilitation
  • Unknown NCT01730183 To Study the Safety and Efficacy of Autologous Bone Marrow Stem Cells in Patients With Spinal Cord Injury
  • Suspended NCT01162915 Transfer of Bone Marrow Derived Stem Cells for the Treatment of Spinal Cord Injury
  • Unknown NCT02034669 Transplantation of Autologous Adipose Derived Stem Cells (ADSCs) in Spinal Cord Injury Treatment
  • Unknown NCT01231893 Transplantation of Autologous Olfactory Ensheathing Cells in Complete Human Spinal Cord Injury
  • Terminated NCT00695149 Treatment for Acute Spinal Cord Injury
  • Completed NCT04288934 Treatment of Spinal Cord Injuries With (AutoBM-MSCs)vs (WJ-MSCs).
  • Completed NCT01354483 Umbilical Cord Blood Mononuclear Cell Transplant to Treat Chronic Spinal Cord Injury

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".