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SCI Clinical Trials in Kentucky

43 spinal cord injury clinical trials list a study site in Kentucky, and 13 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Kentucky or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

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Browse SCI trials by what they study

Open and recruiting (13)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT07147296

    ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

    Empower BP is a pivotal, interventional, multicenter, prospective, randomized, controlled double-blinded study to evaluate the safety and effectiveness of the ARC-IM System in managing symptomatic blood pressure instability in individuals with chronic SCI (\>1 year after SCI).

    Epidural StimulationBlood Pressure
    13 US sites · Arkansas, Colorado, Florida, Georgia…
  • RecruitingNCT04520178

    Effects of 5HTP on the Injured Human Spinal Cord

    This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity.

    Rehabilitation
    2 US sites · Kentucky
  • RecruitingNCT06520020

    Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study

    The study will be a non-randomized, non-blinded pilot study to analyze the safety and feasibility of a non-significant risk device, transcutaneous spinal cord stimulation. The aim is to include 30 total patients, 10 patients in each of 3 groups: 1.

    Transcutaneous Stimulation
    1 US site · Kentucky
  • Enrolling by invitationNCT04077346

    Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury

    Spinal cord injury (SCI) results in damage to the descending neural pathways and leads to the immediate dysfunction of multiple physiological systems below the level of injury. Like adults, children with SCI suffer from neuromuscular paralysis which results in the inability to sit, stand, and walk.

    Transcutaneous StimulationWalking Function
    1 US site · Kentucky
  • RecruitingNCT07504055

    Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

    The goal of this clinical trial is to learn if non-invasive spinal cord stimulation intervention improves blood pressure regulation in individuals with chronic spinal cord injury.

    Transcutaneous StimulationBlood Pressure
    2 US sites · Kentucky
  • Enrolling by invitationNCT06489106

    Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury

    The main goal of this pilot study is to find the best ways to use transcutaneous spinal cord stimulation (scTS) to improve hand function in children with spinal cord injuries (SCI).

    Transcutaneous StimulationHand Movement
    1 US site · Kentucky
  • RecruitingNCT05426681

    Spinal Cord Injury Neuroprotection With Glyburide

    To assess the safety and efficacy of using oral Glyburide (Diabeta) as a neuroprotective agent in patients with acute cervical or thoracic traumatic spinal cord injury.

    Safety
    1 US site · Kentucky
  • RecruitingNCT00178724

    Spinal Cord Injury Registry - North American Clinical Trials Network

    The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI).

    ObservationalRehabilitation
    14 US sites · Florida, Kentucky, Louisiana, Maryland…
  • RecruitingNCT05178056

    Spinal Cord Stimulation and Respiration After Injury

    Respiratory motor control deficit is the leading cause of morbidity and mortality in patients with spinal cord injury. The long-term goal of this NIH-funded study is to develop a rehabilitation strategy for respiration in patients with spinal cord injury as a standard of care.

    Epidural StimulationBreathing Function
    1 US site · Kentucky
  • RecruitingNCT06019949

    Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

    Respiratory complications are among the leading causes of death in patients with chronic spinal cord injury (SCI). Our previous work showed that pulmonary function can be improved by using our original respiratory training method.

    Transcutaneous StimulationBreathing Function
    1 US site · Kentucky
  • RecruitingNCT06243211

    Spinal Decompression Plus Nerve Graft Implantation Following TSCI

    This is a single-blinded (with outcome assessors blinded to treatment allocation), 12-month pilot study to evaluate of the safety, feasibility, and preliminary efficacy of dorsal myelotomy and expansive duraplasty performed either without or with autologous nerve graft implantation after acute…

    Regeneration
    1 US site · Kentucky
  • Enrolling by invitationNCT04032990

    Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury

    Children who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.

    Transcutaneous StimulationArm MovementHand Movement
    1 US site · Kentucky
  • RecruitingNCT06808035

    Understanding Perinatal Spinal Cord Injury

    The purpose of this study is to deepen our understanding of children who have a cervical spinal cord injury obtained in utero or at birth and examine the effects of tailored activity-based recovery training (ABRT) in combination with transcutaneous spinal cord stimulation (scTS).

    RehabilitationTranscutaneous Stimulation
    1 US site · Kentucky

Running, but closed to new participants (4)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT03998527

    Non-Invasive Spinal Cord Stimulation After Injury

    The goal of this study is to assess the function of the lungs and the muscles are used to breathe after individuals receive respiratory training, spinal cord stimulation, a combination of respiratory training and stimulation, a combination of arm training and stimulation, or a combination of trunk…

    Transcutaneous StimulationArm MovementBreathing Function
    1 US site · Kentucky
  • Active, not recruitingNCT03452007

    SPARC Bladder Mapping and Training Study

    The investigators propose to determine the electrode configurations that promote functional gains in the storage and voiding phases of lower urinary tract function as a result of activation of spinal circuits with spinal cord epidural stimulation in humans with spinal cord injury.

    Bladder Function
    1 US site · Kentucky
  • Active, not recruitingNCT04123847

    Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation

    This study will determine the level of functional gain, below the injury for voluntary control of movements, and recovery standing and stepping function as a result of activation of spinal circuits with scES in humans with severe paralysis.

    Epidural StimulationWalking Function
    1 US site · Kentucky
  • Active, not recruitingNCT04105114

    Transformation of Paralysis to Stepping

    The main goal of the project is to develop multiple noninvasive neuromodulatory strategies to facilitate full weight bearing stepping overground in people with paralysis.

    Transcutaneous StimulationWalking Function
    1 US site · Kentucky

Completed and closed (26)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Withdrawn NCT04843137 Acute Mechanisms of Cervical Transcutaneous Electrical Stimulation of the Spinal Cord
  • Completed NCT02731027 Biomarkers of Spontaneous Recovery From Traumatic Spinal Cord Injury
  • Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
  • Suspended NCT04000919 Effects of 5HTP and LDOPA on CNS Excitability After SCI
  • Terminated NCT04586777 Effects of Transvertebral Direct Current Stimulation in Humans
  • Completed NCT02339233 Epi Stim to Facilitate Standing and Stepping
  • Completed NCT03931408 Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections
  • Completed NCT02201173 Health Outcomes After Locomotor Training in Spinal Cord Injury
  • Unknown NCT03949660 Improving Bowel Function and Quality of Life After Spinal Cord Injury
  • Terminated NCT03954496 Improving Hand Recovery With Neuromodulation in Tetraplegia
  • Completed NCT02154412 Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury
  • Terminated NCT04581525 Modulating Neuropathic Pain With Transcranial Direct Current Stimulation
  • Completed NCT05091463 Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI
  • Unknown NCT03559036 Pediatric Locomotor Training Bladder Study
  • Completed NCT04193709 Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
  • Completed NCT03036527 Recovery of Bladder and Sexual Function After Spinal Cord Injury
  • Completed NCT02037620 Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury
  • Completed NCT02396823 Respiratory Motor Control and Blood Pressure Regulation After Spinal Cord Injury
  • Terminated NCT01597518 Riluzole in Spinal Cord Injury Study
  • Completed NCT04295538 Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)
  • Completed NCT00876889 Safety of Riluzole in Patients With Acute Spinal Cord Injury
  • Completed NCT04683848 Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Completed NCT01502631 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
  • Unknown NCT03364660 Task-specific Epidural Stimulation Study
  • Completed NCT03975634 Transcutaneous Spinal Stimulation: Safety and Feasibility for Trunk Control in Children With Spinal Cord Injury

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".