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SCI Clinical Trials in Maryland

48 spinal cord injury clinical trials list a study site in Maryland, and 10 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Maryland or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in Maryland: inpatient SCI rehab facilities in Maryland · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (10)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • Not yet recruitingNCT07799532

    A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

    The goal of this clinical trial is to learn if NVG-291 can improve function in adults with chronic cervical motor-incomplete spinal cord injury. It will also learn about the safety of NVG-291.

    DrugsSafetyBlood PressureHand MovementMotor FunctionQuality of LifeSpasticityTemperature Control
    18 US sites · Alabama, California, Colorado, Connecticut…
  • RecruitingNCT07147296

    ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

    Empower BP is a pivotal, interventional, multicenter, prospective, randomized, controlled double-blinded study to evaluate the safety and effectiveness of the ARC-IM System in managing symptomatic blood pressure instability in individuals with chronic SCI (\>1 year after SCI).

    Epidural StimulationBlood Pressure
    13 US sites · Arkansas, Colorado, Florida, Georgia…
  • RecruitingNCT05726591

    Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

    Background: People with cerebral palsy, spina bifida, muscular dystrophy, or spinal cord injury often have muscle weakness and problems controlling how their legs move. This can affect how they walk. The NIH has designed a robotic device (exoskeleton) that can be worn on the legs while walking.

    Exoskeleton
    1 US site · Maryland
  • RecruitingNCT07521930

    Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

    The goal of this clinical trial is to evaluate the safety and preliminary efficacy of an implantable device that records and stimulates different areas of the brain to allow adults affected by disabling paralysis (see Eligibility for more details) to control and receive feedback from assistive…

    Brain Machine Interface (BMI)
    1 US site · Maryland
  • RecruitingNCT03161067

    Investigation on the Bidirectional Cortical Neuroprosthetic System

    The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the NeuroPort BioPotential Signal Processing System, and the CereStim C96 Programmable Stimulator.

    Brain StimulationArm MovementHand Movement
    1 US site · Maryland
  • RecruitingNCT06288763

    Nerve Transfer to Improve Function in High Level Tetraplegia

    The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.

    Arm MovementHand Movement
    10 US sites · California, Florida, Maryland, Michigan…
  • RecruitingNCT00178724

    Spinal Cord Injury Registry - North American Clinical Trials Network

    The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI).

    ObservationalRehabilitation
    14 US sites · Florida, Kentucky, Louisiana, Maryland…
  • RecruitingNCT02991690

    Systemic Hypothermia in Acute Cervical Spinal Cord Injury

    This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33ºC) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord Injury (SCI).

    Safety
    7 US sites · Arizona, Florida, Georgia, Indiana…
  • RecruitingNCT06998134

    Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

    People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs. The NIH designed a new brace device, called an exoskeleton, that is worn on the legs and helps people walk.

    DevicesElectrical StimulationExoskeletonFunctional Electrical Stimulation (FES)ObservationalLeg MovementWalking Function
    1 US site · Maryland
  • RecruitingNCT06242873

    Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury

    Aim 1: Determine the safety and feasibility of administration of TSCS to children in a clinical setting. Participants will be randomly assigned to experimental (TSCS) or control (sham stimulation) groups. Both groups will receive eight-weeks of individualized gait training.

    Transcutaneous StimulationWalking Function
    1 US site · Maryland

Running, but closed to new participants (1)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT05653206

    Incomplete Cervical SCI Without Instability

    A multicenter, international, prospective, observational case series patient cohort with incomplete cervical SCI without instability will be enrolled to obtain information and data that could inform the feasibility of administering a set of additional core and optional outcome assessments in…

    ObservationalSurgical ProcedureArm MovementHand MovementPain ManagementTrunk ControlWalking Function
    10 US sites · California, Maryland, Wisconsin

Completed and closed (37)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT03197675 Acupuncture in Spinal Cord Injury Subjects
  • Terminated NCT02774603 Aquatic vs. Land Locomotor Training Overground Locomotor Training in Improving Ambulatory Function and Health-Related Quality of Life
  • Terminated NCT01440452 CNS Growth Factors Release and Changes in the Inflammatory Environment in Response to Electrical Stimulation in Subjects With Inflammatory Myelopathies
  • Completed NCT01407354 Comparison of Lokomat and Aquatic Exercise for Individuals With Chronic Incomplete Spinal Cord Injury
  • Terminated NCT03843073 Connected Catheter- Safety and Effectiveness Study
  • Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
  • Completed NCT03137394 Development of a Model of Shoulder Pain Following Spinal Cord Injury
  • Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
  • Completed NCT01961557 Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
  • Completed NCT04523636 Evaluation of Splinting in Tetraplegia
  • Completed NCT06850363 ExaStim Upper Limb Home Use Clinical Validation Study
  • Completed NCT02314221 Exoskeletal-assisted Walking to Improve Mobility, Bowel Function and Cardio-Metabolic Profiles in Persons With SCI
  • Completed NCT00245726 Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)
  • Completed NCT01479777 Functional Electrical Stimulation (FES) Driven Stepping in Individuals With Spinal Cord Injury
  • Completed NCT03854214 Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
  • Completed NCT03111277 MR Guided Focused Ultrasound for Treatment of Neuropathic Pain
  • Completed NCT00001361 Magnetic Resonance Imaging Studies of Motor and Thought Processes
  • Completed NCT00001661 Mechanisms of Human Plasticity in the Human System
  • Completed NCT00055588 Nervous System Function in Normal Volunteers During Cycling Training
  • Completed NCT00001216 Non-Invasive Electrical Stimulation of the Human Brain
  • Terminated NCT01005615 Patterned Functional Electrical Stimulation (FES) Ergometry of Arm and Shoulder in Individuals With Spinal Cord Injury
  • Completed NCT00011544 Physical Performance Measures for Manual Wheelchair Users
  • Completed NCT02878850 Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury
  • Terminated NCT01597518 Riluzole in Spinal Cord Injury Study
  • Completed NCT00385918 Robotically Assisted Treadmill Training in Spinal Cord Injury (SCI)
  • Completed NCT01217008 Safety Study of GRNOPC1 in Spinal Cord Injury
  • Terminated NCT00531466 Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury
  • Completed NCT00876889 Safety of Riluzole in Patients With Acute Spinal Cord Injury
  • Terminated NCT02163876 Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury
  • Terminated NCT03762655 Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
  • Terminated NCT01217047 Study on Functional Electrical Stimulation (FES) Cycling Following Spinal Cord Injury
  • Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Unknown NCT00475748 Surgical Management of Spinal Cord Injuries In Neck
  • Withdrawn NCT03046875 The Biophysical Impact of Transcutaneous Spinal Cord Stimulation Within a Single Session
  • Completed NCT03384017 The Impact of Transcutaneous Spinal Cord Stimulation (TSCS) and Gait Training on Walking Function in Patients With Spinal Cord Injury
  • Completed NCT02943915 The WISE Trial - Walking Improvement for SCI With Exoskeleton
  • Completed NCT01491789 Virtual Sailing Simulator in Individuals With Spinal Cord Injury

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".