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SCI Clinical Trials in Michigan

48 spinal cord injury clinical trials list a study site in Michigan, and 10 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Michigan or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in Michigan: inpatient SCI rehab facilities in Michigan · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (10)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • Not yet recruitingNCT07799532

    A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

    The goal of this clinical trial is to learn if NVG-291 can improve function in adults with chronic cervical motor-incomplete spinal cord injury. It will also learn about the safety of NVG-291.

    DrugsSafetyBlood PressureHand MovementMotor FunctionQuality of LifeSpasticityTemperature Control
    18 US sites · Alabama, California, Colorado, Connecticut…
  • RecruitingNCT07357428

    Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

    The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI).

    Brain Machine Interface (BMI)
    3 US sites · California, Massachusetts, Michigan
  • RecruitingNCT06596291

    Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

    This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A in male and female adult participants with Neurogenic Detrusor Overactivity (NDO)-related incontinence following Spinal Cord Injury (SCI),…

    Bladder Function
    5 US sites · California, Michigan, Ohio, Pennsylvania…
  • RecruitingNCT05536076

    Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury

    It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A. the largest integrated health care system in the world for spinal cord injuries injury care.

    Breathing Function
    1 US site · Michigan
  • RecruitingNCT07171489

    Efficacy of a Wearable Noninvasive Neuromodulation Device

    The aim of this study is to investigate the potential of transcutaneous neuromodulation (TNM) to treat slow colonic transit and constipation, termed the Neurogenic bowel dysfunction (NBD), in people with SCI.

    Electrical StimulationBowel Function
    1 US site · Michigan
  • RecruitingNCT05023772

    Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

    The purpose of this research is to combine two complementary modes of treatment, spinal interstitial laser ablation and stereotactic spine radiosurgery (SSRS) for the treatment for spinal tumors near the spinal cord with an objective to improve tumor control, improve pain control, preserve…

    Pain ManagementQuality of Life
    1 US site · Michigan
  • Not yet recruitingNCT07227285

    Long-term Follow-up Study of Patients Who Received EG110A, a Non-replicative Herpes Simplex Virus 1-derived Gene Therapy

    The aim of this study is to continue following participants who have received EG110A during five years to know how it is tolerated in humans, any side-effects it may cause and what might be an effective dose over five years.

    DrugsBladder Function
    4 US sites · California, Michigan, Pennsylvania, Texas
  • RecruitingNCT05351827

    Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

    The prevalence of autonomic dysfunction and sleep disordered breathing (SDB) is increased in individuals with spinal cord injury (SCI).

    Intermittent HypoxiaBlood Pressure
    1 US site · Michigan
  • RecruitingNCT06288763

    Nerve Transfer to Improve Function in High Level Tetraplegia

    The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.

    Arm MovementHand Movement
    10 US sites · California, Florida, Maryland, Michigan…
  • RecruitingNCT02922894

    Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

    This study will investigate potential therapeutic approaches for sleep-disordered breathing (SDB) in patients with chronic cervical spine injury (\>6 months post-injury).

    Breathing Function
    1 US site · Michigan

Running, but closed to new participants (3)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT05339932

    Grand Valley State University (GVSU) Skills on Wheels

    Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them.

    Observational
    1 US site · Michigan
  • Active, not recruitingNCT04023591

    Nerve Transfer After Spinal Cord Injury- Multi-center

    Current treatment strategies of acute cervical spinal cord injuries remain limited. Treatment options that provide meaningful improvements in patient quality of like and long-term functional independence will provide a significant public health impact.

    Hand Movement
    9 US sites · California, Florida, Michigan, Missouri…
  • Active, not recruitingNCT05117827

    Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

    For children who use a power wheelchair, a powered wheelchair standing device (PWSD) may be considered for daily use. A PWSD allows a child to electronically move between sitting and standing and can be driven in either position.

    Observational
    1 US site · Michigan

Completed and closed (35)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT00407745 A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
  • Completed NCT00557973 A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury
  • Completed NCT01337908 A Study of Mood and Stress After Spinal Cord Injury
  • Terminated NCT00712322 A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity
  • Completed NCT06098170 Acceptance and Commitment Therapy for Chronic Pain in SCI: Development and Testing of an eHealth Program
  • Completed NCT02341950 Clinical Trial of a Serious Game for Individuals With SCI/D
  • Completed NCT00318591 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections
  • Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
  • Completed NCT07663266 Development of Pain Management JITAI Content in Multiple Sclerosis and Spinal Cord Injury
  • Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
  • Completed NCT04384172 Effect of Peripheral Neuromodulation on Vaginal Blood Flow
  • Completed NCT01920243 Evaluation of a Bowel and Bladder Health Management Program for Individuals With Spinal Cord Injury (SCI)
  • Completed NCT03503513 Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury
  • Completed NCT01882257 Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
  • Unknown NCT03914677 Mecamylamine for Autonomic Dysreflexia Prophylaxis
  • Unknown NCT03736382 Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
  • Completed NCT00860951 P300 Brain Computer Interface Keyboard to Operate Assistive Technology
  • Completed NCT02616081 Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
  • Completed NCT04872569 Pilot Testing A Pregnancy Decision Making Tool for Women With Spinal Cord Injury (SCI)
  • Completed NCT00592384 Project to Improve Symptoms and Mood in People With Spinal Cord Injury
  • Unknown NCT03390140 ReInventing Yourself After SCI: an Intervention to Improve Outcomes After Spinal Cord Injury
  • Completed NCT02458469 Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI
  • Completed NCT04295538 Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)
  • Completed NCT00041717 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT04096950 Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury
  • Completed NCT03168828 Safety and Tolerability of TAR-302-5018 in Subjects With Neurogenic Detrusor Overactivity Resulting From Spinal Cord Injury
  • Completed NCT02176928 Sleep-Disordered Breathing in Chronic SCI
  • Terminated NCT02163876 Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury
  • Completed NCT04683848 Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Completed NCT02943915 The WISE Trial - Walking Improvement for SCI With Exoskeleton
  • Completed NCT00735670 Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury
  • Completed NCT02830074 Treatment of Sleep-disordered Breathing in Patients With SCI
  • Completed NCT03430375 Wheelchair Cushion Comparison Study: SAFETY

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".