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SCI Clinical Trials in Minnesota

55 spinal cord injury clinical trials list a study site in Minnesota, and 15 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Minnesota or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in Minnesota: inpatient SCI rehab facilities in Minnesota · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (15)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT07147296

    ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

    Empower BP is a pivotal, interventional, multicenter, prospective, randomized, controlled double-blinded study to evaluate the safety and effectiveness of the ARC-IM System in managing symptomatic blood pressure instability in individuals with chronic SCI (\>1 year after SCI).

    Epidural StimulationBlood Pressure
    13 US sites · Arkansas, Colorado, Florida, Georgia…
  • RecruitingNCT07210411

    Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

    The purpose of this research is to learn about how the participant's body is able to balance changes in blood pressure, and how spinal cord stimulation affects these changes as well as immune \& cardiovascular function in participants with spinal cord injury.

    Transcutaneous StimulationBlood Pressure
    1 US site · Minnesota
  • RecruitingNCT06410001

    CE-STAND: Cervical Epidural STimulation After Neurologic Damage

    CE-STAND aims to address three areas under-represented in research: chronic, cervical, and autonomic dysfunction. It is both significant and highly impactful, as treating autonomic dysfunction could substantially improve function and quality of life (QoL) in chronic cervical SCI patients.

    Epidural StimulationBlood Pressure
    1 US site · Minnesota
  • RecruitingNCT07012135

    Deciphering Preserved Autonomic Function After Multiple Sclerosis

    This study looks to characterize gradients of dysfunction in the autonomic nervous system in patients with clinically diagnosed multiple sclerosis.

    Bladder FunctionBlood Pressure
    1 US site · Minnesota
  • RecruitingNCT04493372

    Deciphering Preserved Autonomic Function After Spinal Cord Injury

    This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically…

    Blood Pressure
    1 US site · Minnesota
  • RecruitingNCT07029802

    Development of a Novel Evaluation Scale of Mental Body Representation (MBR) for Adults With Spinal Cord Injury

    The purpose of this study is twofold: (1) Develop a new evaluation scale for mental body representations (MBR, i.e., body awareness and visuospatial body maps) for adults with spinal cord injury (SCI) with and without neuropathic pain.

    ObservationalPain Management
    1 US site · Minnesota
  • Not yet recruitingNCT07619300

    Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage

    The purpose of this study is to study sensorimotor circuit activity generated in response to temporarily implanted dorsal root ganglion stimulation by recording from muscles of the lower extremities as well as functional outcomes achieved over a 10-day rehabilitation program in an individual with…

    Electrical StimulationRehabilitation
    1 US site · Minnesota
  • RecruitingNCT03026816

    Epidural Stimulation After Neurologic Damage

    This study will evaluate a method to optimize parameter settings in epidural spinal cord stimulation used to recover lower extremity volitional movement.

    Epidural Stimulation
    1 US site · Minnesota
  • RecruitingNCT05705453

    Epidural Stimulation After Neurologic Damage: Long-Term Outcomes

    This study will evaluate the long-term effect of chronic spinal cord stimulation to restore volitional movement for patients with chronic spinal cord injuries.

    Epidural Stimulation
    1 US site · Minnesota
  • RecruitingNCT07210437

    Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI

    The purpose of this research is to learn about how the body is able to balance changes in blood pressure, how that changes over time, and how these changes impact a participant's risk of developing medical problems.

    Blood PressureTrunk Control
    1 US site · Minnesota
  • RecruitingNCT05776030

    Multi-speed Ergonomic Wheelchair

    Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain.

    DevicesPain ManagementQuality of Life
    1 US site · Minnesota
  • Not yet recruitingNCT07099625

    Optimization of Adaptive Rowing Seating

    Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities. These activity-based communities are medicine free treatment systems enhancing Veterans' health from a holistic perspective.

    Rehabilitation
    2 US sites · Minnesota, Ohio
  • RecruitingNCT07384052

    Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury

    The purpose of this study is to find out whether insulin, a drug approved by the FDA for the treatment of diabetes mellitus, is safe when administered as a nasal spray (intranasally) to people who have experienced a spinal cord injury.

    Drugs
    1 US site · Minnesota
  • RecruitingNCT05741788

    The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

    Spinal cord stimulation modulates the nervous system to effectively block pain signals originating from the back and legs. Spinal cord stimulation has been shown to improve chronic pain, improve quality of life, and reduce disability.

    Electrical StimulationPain ManagementQuality of Life
    1 US site · Minnesota
  • RecruitingNCT06140355

    cHAnging the Perceived Pain INtensity in divErSe Populations With Spinal Cord Injury

    Chronic neuropathic pain affects 69% of adults with spinal cord injury (SCI). Current treatment options are limited (primarily pain medications) with insufficient benefits and significant risks for addiction and adverse effects.

    Pain Management
    3 US sites · Florida, Minnesota, Texas

Running, but closed to new participants (2)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT04520373

    Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients

    The purpose of this research study is to investigate the safety and potential therapeutic effects of autologous, culture-expanded, adipose derived mesenchymal stem cell intrathecal injections in the treatment of spinal cord injury.

    Regeneration
    1 US site · Minnesota
  • Active, not recruitingNCT02600910

    Natural History of Shoulder Pathology in Manual Wheelchair Users

    Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pain that greatly affect quality of life and level of independence.

    Arm Movement
    2 US sites · Minnesota, Texas

Completed and closed (38)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT05167032 A Clinical Trial of Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery in Adults With Spinal Cord Injury
  • Completed NCT03696927 Active Powered Prosthesis (APEX) for Spinal Cord Injury
  • Terminated NCT03261388 Activity Based Locomotor Exercise PrOgram-Wait-list controllEd Research
  • Completed NCT03308565 Adipose Stem Cells for Traumatic Spinal Cord Injury
  • Completed NCT02700178 Biofeedback for Wheelchair Users
  • Completed NCT05639946 Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
  • Completed NCT04379011 Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
  • Completed NCT04309864 CMAP Refinement for Pressure Injury Prevention
  • Terminated NCT04917107 CREATION: A Clinical Trial of Qigong for Neuropathic Pain Relief in Adults With Spinal Cord Injury
  • Completed NCT04378218 Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia
  • Completed NCT00318591 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections
  • Completed NCT00047580 Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
  • Completed NCT03626324 Connected Catheter (C2P) Study for Bladder Management
  • Terminated NCT03843073 Connected Catheter- Safety and Effectiveness Study
  • Completed NCT04736849 Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury
  • Completed NCT04706208 Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
  • Completed NCT05284201 LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury
  • Completed NCT04668326 Mobile Manual Standing Wheelchair for SCI
  • Completed NCT03987243 Mobile and Remote Monitoring of Seating Pressure for Wheelchair Users With SCI
  • Completed NCT03082898 Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Clinical Setting (SC140121 Study 1 and 2)
  • Withdrawn NCT04149769 Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Home and Community Setting (SC140121 Study 3)
  • Completed NCT02616081 Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
  • Completed NCT03392155 Performance and Nutrition Program for Athletes in Adaptive Sports
  • Completed NCT02658656 Powered Exoskeletons in Persons With SCI
  • Completed NCT05870189 Remotely Delivered Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery After Spinal Cord Injury
  • Terminated NCT01597518 Riluzole in Spinal Cord Injury Study
  • Completed NCT02777281 Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI
  • Completed NCT00041717 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT05095454 Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI
  • Completed NCT05301335 Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
  • Completed NCT05376449 Spinal Cord Injury - Exercise
  • Completed NCT02592668 Spinal Cord Injury Epidural Stimulation
  • Terminated NCT02163876 Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury
  • Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Completed NCT04964362 The Impact of Injustice Appraisals on Psychosocial Outcomes Following Spinal Cord Injury: A Longitudinal Study
  • Completed NCT04697472 The Up-LIFT Study of Non-Invasive ARC Therapy for Spinal Cord Injury
  • Completed NCT02943915 The WISE Trial - Walking Improvement for SCI With Exoskeleton

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".