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SCI Clinical Trials in Missouri

41 spinal cord injury clinical trials list a study site in Missouri, and 7 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Missouri or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in Missouri: inpatient SCI rehab facilities in Missouri · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (7)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT06559618

    Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

    This is a Phase 1b study to assess the safety, tolerability, PK, and PD of investigational phage therapy (IP) in adults with SCI and bladder colonization (ASB).

    Bladder Function
    2 US sites · Missouri, Texas
  • RecruitingNCT07386522

    Health Information for Persons With Spinal Cord Injury

    The goal of this pilot study is to design and feasibility test a mobile phone text messaging (SMS) self-management intervention for persons with spinal cord injury (PwSCI).

    Bladder FunctionBowel FunctionPain ManagementPressure SoresQuality of Life
    1 US site · Missouri
  • RecruitingNCT06529094

    Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

    Spinal cord injury (SCI) is a permanent condition affecting every aspect of life including health, daily activities, and participation and quality of life. Persons with SCI are at high risk of pressure injury (PrI) throughout their lives due to loss of sensation, nerve damage and immobility.

    ObservationalPressure Sores
    7 US sites · California, Florida, Illinois, Missouri…
  • RecruitingNCT06288763

    Nerve Transfer to Improve Function in High Level Tetraplegia

    The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.

    Arm MovementHand Movement
    10 US sites · California, Florida, Maryland, Michigan…
  • RecruitingNCT07488793

    Remote Ischemic Conditioning for PwSCI

    The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI).

    RehabilitationQuality of Life
    1 US site · Missouri
  • RecruitingNCT07397559

    Spatiotemporal tSCS in Spinal Cord Injury

    Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in muscle recruitment compared to invasive approaches limits the type of…

    ObservationalTranscutaneous StimulationLeg Movement
    1 US site · Missouri
  • RecruitingNCT05472584

    Spinal Cord Stimulation and Training

    This study will help the investigators better understand the changes in short-term excitability and long-term plasticity of corticospinal, reticulospinal and spinal neural circuits and how the changes impact the improvements of spinal cord stimulation (SCS) mediated motor function.

    Transcutaneous Stimulation
    1 US site · Missouri

Running, but closed to new participants (2)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT04457206

    Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease

    The investigator is evaluating data stored on the Collaborative Community Clinic data repository (IRB #201811032). Researchers seek to evaluate the effectiveness of the Collaborative Community Clinic (CCC), an occupational therapy student experiential learning clinic for uninsured or under-insured…

    ObservationalRehabilitationMental HealthQuality of Life
    1 US site · Missouri
  • Active, not recruitingNCT04023591

    Nerve Transfer After Spinal Cord Injury- Multi-center

    Current treatment strategies of acute cervical spinal cord injuries remain limited. Treatment options that provide meaningful improvements in patient quality of like and long-term functional independence will provide a significant public health impact.

    Hand Movement
    9 US sites · California, Florida, Michigan, Missouri…

Completed and closed (32)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Terminated NCT00712322 A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity
  • Completed NCT04009187 A Wheelchair Propulsion Training Program
  • Completed NCT04893590 Adapting MHealth Technology to Improve Patient Activation
  • Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
  • Completed NCT03985553 Development of a Self- Management Program for Parents With Spinal Cord Injury and Disease
  • Completed NCT03296592 Diffusion MRI in Cervical Spondylotic Myelopathy (CSM)
  • Withdrawn NCT01712698 Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries
  • Completed NCT02302157 Dose Escalation Study of AST-OPC1 in Spinal Cord Injury
  • Completed NCT03727893 Exercise Training and Manual Wheelchair Users With SCI
  • Completed NCT04007445 Exercise for People with Spinal Cord Injury
  • Completed NCT03941600 Feasibility of Exercise and Spinal Cord Injury
  • Completed NCT03781609 Motor Learning Approach for Manual Wheelchair Users
  • Completed NCT04422769 Needs of Persons with Spinal Cord Injury (SCI)
  • Completed NCT01714349 Nerve Transfer After Spinal Cord Injuries
  • Withdrawn NCT02861612 Nerve Transfers to Restore Hand Function in Spinal Cord Injury
  • Terminated NCT05354206 Neural Facilitation of Movements in People With SCI
  • Terminated NCT00101361 Oxandrolone to Heal Pressure Ulcers
  • Completed NCT02658656 Powered Exoskeletons in Persons With SCI
  • Terminated NCT03655080 Pulsed Abraxane and Radiotherapy for Improving and Maintaining Ambulation After Cancer-Related Cord Compression
  • Terminated NCT01597518 Riluzole in Spinal Cord Injury Study
  • Completed NCT04295538 Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)
  • Completed NCT00041717 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT04096950 Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury
  • Completed NCT00117806 Spinal Cord Injury Vocational Integration Program (SCI-VIP)
  • Completed NCT04683848 Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Completed NCT01502631 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
  • Completed NCT03464409 Supporting Patient Decisions About UE Surgery in Cervical SCI
  • Completed NCT04995796 Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI
  • Unknown NCT00624988 The Effect of Vibration Therapy on the Bone Density of the Tiba in Patients With Spinal Cord Injury
  • Completed NCT01899664 Upper Extremity Surgery in Spinal Cord Injury

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".