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SCI Clinical Trials in North Carolina

32 spinal cord injury clinical trials list a study site in North Carolina, and 5 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in North Carolina or several. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.

Also in North Carolina: inpatient SCI rehab facilities in North Carolina · adaptive sports and support organizations · wheelchair van dealers

Browse SCI trials by what they study

Open and recruiting (5)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • Not yet recruitingNCT07799532

    A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

    The goal of this clinical trial is to learn if NVG-291 can improve function in adults with chronic cervical motor-incomplete spinal cord injury. It will also learn about the safety of NVG-291.

    DrugsSafetyBlood PressureHand MovementMotor FunctionQuality of LifeSpasticityTemperature Control
    18 US sites · Alabama, California, Colorado, Connecticut…
  • RecruitingNCT06288763

    Nerve Transfer to Improve Function in High Level Tetraplegia

    The goal of this observational study is to determine if nerve transfer surgeries improve upper extremity function and quality of life in patients with a high level cervical spinal cord injury.

    Arm MovementHand Movement
    10 US sites · California, Florida, Maryland, Michigan…
  • RecruitingNCT05491525

    Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC

    The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC

    DrugsBladder Function
    38 US sites · Arkansas, California, Colorado, Florida…
  • RecruitingNCT05458947

    Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)

    To examine the effects of Physical Therapist (PT) wound care modalities (pulsed wound irrigation (PWI) + electrical stimulation (ES), PWI only, and ES only) on wound healing in patients with spinal cord injuries (SCI).

    Pressure Sores
    1 US site · North Carolina
  • RecruitingNCT00178724

    Spinal Cord Injury Registry - North American Clinical Trials Network

    The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI).

    ObservationalRehabilitation
    14 US sites · Florida, Kentucky, Louisiana, Maryland…

Running, but closed to new participants (1)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT04894734

    Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI)

    The purpose of this feasibility study is to compare the impact of Spinal cord stimulation \[SCS\] for Spinal Cord Injury (SCI) pain and rehabilitation. SCS, also known as Epidural Electrical Stimulation (EES), will be utilized along with conventional medical management (CMM) or CMM alone.

    Epidural StimulationPain Management
    1 US site · North Carolina

Completed and closed (26)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT00407745 A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
  • Completed NCT00224029 A Study Evaluating Oxybutynin in Patients With Neurogenic Overactive Bladder Associated With a Neurological Condition
  • Completed NCT00318591 Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections
  • Terminated NCT01433159 Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury
  • Completed NCT00628446 Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
  • Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
  • Completed NCT01025609 Dietary Patterns and Cardiovascular (CVD) Risk in Spinal Cord Injury (SCI) Factors In Individuals With Chronic Spinal Cord Injury
  • Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
  • Completed NCT03457558 Food Security and Perceptions and Barriers to Healthy Eating in Individuals With Spinal Cord Injuries
  • Unknown NCT04453943 Modeling, Optimization, and Control Methods for a Personalized Hybrid Walking Exoskeleton
  • Completed NCT02368405 Nutrition Education for Cardiovascular Disease Prevention in Spinal Cord Injury
  • Completed NCT02878850 Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury
  • Terminated NCT02163551 Respiratory Event-Related Potentials in Patients With Spinal Cord Injury
  • Completed NCT04295538 Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)
  • Completed NCT00041717 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
  • Completed NCT04096950 Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury
  • Terminated NCT00531466 Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury
  • Completed NCT03168828 Safety and Tolerability of TAR-302-5018 in Subjects With Neurogenic Detrusor Overactivity Resulting From Spinal Cord Injury
  • Completed NCT05301335 Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
  • Terminated NCT03762655 Study of Probable Benefit of the Neuro-Spinal Scaffold™ in Subjects With Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
  • Completed NCT04683848 Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
  • Completed NCT01243125 Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation
  • Completed NCT01502631 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
  • Terminated NCT02138110 The INSPIRE Study: Probable Benefit of the Neuro-Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury
  • Unknown NCT05249595 Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".