SCI Clinical Trials in Ohio
83 spinal cord injury clinical trials list a study site in Ohio, and 23 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in Ohio or several. Last refreshed 2026-09-12.
Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.
Also in Ohio: inpatient SCI rehab facilities in Ohio · adaptive sports and support organizations · wheelchair van dealers
Browse SCI trials by what they study
- Rehabilitation (568)
- Devices (359)
- Observational (319)
- Drugs (283)
- Electrical Stimulation (213)
- Transcutaneous Stimulation (148)
- Exoskeleton (129)
- Surgical Procedure (103)
- Functional Electrical Stimulation (FES) (89)
- Epidural Stimulation (81)
- Nutrition (79)
- Brain Stimulation (69)
- Safety (67)
- Stem Cells (52)
- Transcranial Magnetic Stimulation (TMS) (44)
- Intermittent Hypoxia (38)
- Transcranial Direct Current Stimulation (tDCS) (32)
- Brain Machine Interface (BMI) (30)
- Neuromuscular Electrical Stimulation (NMES) (13)
Open and recruiting (23)
These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.
- RecruitingNCT01474148
A Neuroprosthesis for Seated Posture and Balance
The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate stability of the trunk and hips. FES involves applying small electric currents to the nerves, which cause the muscles to contract.
1 US site · Ohio - RecruitingNCT05626816
Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury
Bowel issues occur in nearly all people after spinal cord injury (SCI) and one major complication is fecal incontinence (accidents). This complication has been repeatedly highlighted by people living with SCI as particularly life-limiting and in need of more options for interventions.
1 US site · Ohio - RecruitingNCT06836739
At-Home Genital Nerve Stimulation for SCI Bowel
The purpose of this study is to test whether electrical stimulation of the skin in the pelvic area (near the genitals) can reduce the reflexes that cause bowel accidents in people with spinal cord injuries. Current bowel treatments either involve diet and medications or surgery.
1 US site · Ohio - RecruitingNCT03023696
Can Prophylactic Foraminotomy Prevent C5 Palsy
C5 palsy (C5P) is a well-known, although rare complication of cervical spine decompression surgery. In severe forms, C5P causes debilitating upper extremity weakness involving the deltoids and/or biceps brachii muscles, ultimately diminishing these patients' quality of life.
1 US site · Ohio - RecruitingNCT07225582
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury.
1 US site · Ohio - Not yet recruitingNCT07668063
Device for Bladder Control for Men With SCI
Urinary incontinence, bladder frequency, and bladder urgency are significant medical problems for people with overactive bladder (OAB) or neurogenic bladder overactivity (NDO).
1 US site · Ohio - RecruitingNCT06882460
Diet and Exercise Solutions to Postprandial Hypotension
The purpose of this study is to determine if a low glycemic diet and lower-body electrical stimulation can reduce postprandial hypotension in individuals with chronic spinal cord injury.
1 US site · Ohio - RecruitingNCT06596291
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A in male and female adult participants with Neurogenic Detrusor Overactivity (NDO)-related incontinence following Spinal Cord Injury (SCI),…
5 US sites · California, Michigan, Ohio, Pennsylvania… - RecruitingNCT05337982
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program.
2 US sites · Ohio - RecruitingNCT07768761
Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis.
1 US site · Ohio - RecruitingNCT00623389
Evaluation of an Advanced Lower Extremity Neuroprostheses
The purpose of this study is to evaluate a surgically implanted functional electrical stimulation (FES) system to facilitate exercise, standing, stepping and/or balance in people with various degrees of paralysis.
2 US sites · Ohio - RecruitingNCT04887688
Exciflex Electroceutical Banadage for Chronic Wound Therapy
Objectives: The study objective is to carry a pilot clinical assessment comparing the exciflex bandage to standard of care (SoC) for ischemic wounds and will involve participants who are Veterans with lower extremity ischemic wounds.
1 US site · Ohio - RecruitingNCT05302999
Feasibility of Early Gabapentin as an Intervention for Neurorecovery
The objective of the proposed study is to conduct the first ever prospective, dose-exploration trial to test the feasibility of early administration of gabapentin as an intervention for neurorecovery.
1 US site · Ohio - Not yet recruitingNCT07640152
Fermented Foods and Bowel Health in SCI
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut health in adults with chronic spinal cord injury (SCI). The study will also evaluate the feasibility and tolerability of consuming fermented foods daily for 10 weeks.
1 US site · Ohio - RecruitingNCT05863754
Grasp-Release Assessment of a Networked Neuroprosthesis Device
The overall objective of this trial is to characterize the safety and effectiveness of the Networked Neuroprosthesis Device - Upper Extremity (NP-UE) in individuals living with cervical SCI.
1 US site · Ohio - RecruitingNCT06965127
Implant for Walking After Incomplete SCI
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in people with incomplete spinal cord injury.
1 US site · Ohio - RecruitingNCT06529094
Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic
Spinal cord injury (SCI) is a permanent condition affecting every aspect of life including health, daily activities, and participation and quality of life. Persons with SCI are at high risk of pressure injury (PrI) throughout their lives due to loss of sensation, nerve damage and immobility.
7 US sites · California, Florida, Illinois, Missouri… - RecruitingNCT02329652
Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury
This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS
1 US site · Ohio - Not yet recruitingNCT07099625
Optimization of Adaptive Rowing Seating
Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities. These activity-based communities are medicine free treatment systems enhancing Veterans' health from a holistic perspective.
2 US sites · Minnesota, Ohio - RecruitingNCT06070233
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to target certain nerves in the back to help loosen up the muscles.
2 US sites · Florida, Ohio - RecruitingNCT06611748
Restoration of Hand Function in Cervical SCI
The purpose of this study is to evaluate a new method of restoring hand function to people with spinal cord injury. Current methods to restore hand function include tendon transfers and nerve transfers.
1 US site · Ohio - Enrolling by invitationNCT04565366
Transforming Research and Clinical Knowledge in Spinal Cord Injury
The overall goal of Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI) study is to determine the relationships among the clinical, neuroimaging, cognitive, genetic and proteomic biomarker characteristics of acute traumatic spinal cord injury (SCI).
5 US sites · California, Ohio, Utah, Washington - RecruitingNCT07738978
Understanding and Enhancing Human Health and Movement
By doing this study, investigators hope to learn how electrical stimulation can improve human movement, biomechanics, and function and to gather information on the safety and effectiveness of an implanted electrical stimulation system after paralysis from spinal cord injury, stroke, multiple…
1 US site · Ohio
Running, but closed to new participants (4)
Active studies that are no longer enrolling. Useful for seeing where the field is heading.
- Active, not recruitingNCT03253952
A Study of Autonomic Dynamic Dysfunction to Predict Infections After Spinal Cord Injury.
The study is designed to investigate whether autonomic shifts (dysautonomia, sympatho-vagal instability) that develop after SCI have value in predicting SCI-associated infections (SCI-AI).
1 US site · Ohio - Active, not recruitingNCT02978638
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation. The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI).
4 US sites · California, New Mexico, Ohio - Active, not recruitingNCT00583804
Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury
The purpose of this study is to evaluate the effectiveness of an implanted stimulator and sensor for providing hand and arm function for individuals with cervical level spinal cord injury.
1 US site · Ohio - Active, not recruitingNCT06440538
Rebuilding Inter-limb Transfer in Cervical SCI
The purpose of this study in people living with cervical Spinal Cord Injury (SCI) is to examine the effects of paired neurostimulation (i.e., PCMS) combined with contralateral motor training on inter-limb transfer of ballistic motor and hand dexterity skills.
1 US site · Ohio
Completed and closed (56)
Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.
- Completed NCT00407745 A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
- Completed NCT01923662 A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
- Completed NCT00500812 A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries
- Terminated NCT00712322 A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity
- Completed NCT06087445 A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia
- Completed NCT03989440 AXER-204 in Participants With Chronic Spinal Cord Injury
- Completed NCT05740527 Ambulatory Closed-loop Stimulation for Bladder Control
- Withdrawn NCT00262457 BIONs, for Improved Tissue Health and Pressure Sore Prevention
- Completed NCT02731027 Biomarkers of Spontaneous Recovery From Traumatic Spinal Cord Injury
- Completed NCT04889092 Blood Flow Restriction Exercise for Those With SCI
- Completed NCT03472599 Chronic Electrical Stimulation to Reduce Bladder Hyperreflexia
- Completed NCT00624806 Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
- Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
- Completed NCT02821845 Eccentric Motor Control After SCI
- Terminated NCT00332319 Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients
- Completed NCT00010374 Electrical Activation of The Diaphragm for Ventilatory Assist
- Completed NCT00011570 Electrical Control of Bladder in Spinal Cord Injury Patients
- Completed NCT00047619 Enhancement of Pressure Healing With Pulsatile Lavage
- Completed NCT04256603 Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI
- Completed NCT00589199 Functional Electrical Stimulation for Production of Artificial Cough
- Completed NCT00890916 Hand Function for Tetraplegia
- Completed NCT05128994 Hand Grasp Function After Spinal Cord Injury
- Completed NCT04075812 High Definition Neuromuscular Stimulation in Tetraplegia
- Completed NCT05214378 High Frequency SARS for Neurogenic Bladder and Bowel Emptying
- Withdrawn NCT00623948 Implanted Gluteal Stimulation System for Pressure Sore Prevention
- Unknown NCT01570816 Improving Ambulatory Community Access After Paralysis
- Completed NCT03892746 Improving SCI Rehabilitation Interventions by Retraining the Brain
- Completed NCT01539109 Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation
- Completed NCT03509571 Ketogenic Diet to Improve Neuro-recovery
- Withdrawn NCT03098927 Mirror Neuron Network Based Motor Imagery Training to Improve Brain Computer Interface Performance in Spinal Cord Injury Patients
- Unknown NCT04900896 Outcome Measures Study on an Adult Myoelectric Elbow-Wrist-Hand Orthosis
- Terminated NCT00101361 Oxandrolone to Heal Pressure Ulcers
- Completed NCT02658656 Powered Exoskeletons in Persons With SCI
- Completed NCT02878850 Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury
- Completed NCT01997125 Reanimation in Tetraplegia
- Completed NCT03439319 Restoration of Reaching and Grasping Function in Individuals With Spinal Cord Injury Using MyndMove® Neuromodulation Therapy
- Completed NCT03482310 Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
- Completed NCT05575674 Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes
- Completed NCT01141647 SCI-VIP: Predictive Outcome Model Over Time for Employment (PrOMOTE)
- Completed NCT00041717 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
- Completed NCT01683838 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
- Completed NCT04096950 Safety and Pharmacokinetics Study of MT-3921 in Spinal Cord Injury
- Terminated NCT02524379 Spinal Cord Injury Neuroprotection With Glyburide
- Completed NCT00117806 Spinal Cord Injury Vocational Integration Program (SCI-VIP)
- Completed NCT00116337 Spinal Cord Stimulation to Restore Cough
- Completed NCT01659541 Stimulation With Wire Leads to Restore Cough
- Completed NCT00004445 Study of an Implantable Functional Neuromuscular Stimulation System for Patients With Spinal Cord Injuries
- Completed NCT04683848 Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
- Terminated NCT02669849 Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
- Completed NCT01502631 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
- Completed NCT07092293 Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
- Completed NCT00995215 Sub-study to Spinal Cord Stimulation to Restore Cough
- Completed NCT02498548 Training of Eccentric Lower Extremity Function After SCI
- Unknown NCT04627168 Trancutaneous Abdominal Stimulation on Bowel Function.
- Completed NCT00006429 Treadmill Training for Spinal Cord Injury
- Completed NCT01236170 Understanding Quality and Equity in Wheelchairs for Veterans
Where this list comes from
Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.
Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".