SCI Clinical Trials in South Carolina
16 spinal cord injury clinical trials list a study site in South Carolina, and 9 are currently open to new participants. Every trial below links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Trial sites are tracked at state level, so a listed trial may run at one hospital in South Carolina or several. Last refreshed 2026-09-12.
Open these in the Trials Finder → Filter by treatment, target, and status, or sort by distance.
Also in South Carolina: inpatient SCI rehab facilities in South Carolina · adaptive sports and support organizations · wheelchair van dealers
Browse SCI trials by what they study
- Rehabilitation (568)
- Devices (359)
- Observational (319)
- Drugs (283)
- Electrical Stimulation (213)
- Transcutaneous Stimulation (148)
- Exoskeleton (129)
- Surgical Procedure (103)
- Functional Electrical Stimulation (FES) (89)
- Epidural Stimulation (81)
- Nutrition (79)
- Brain Stimulation (69)
- Safety (67)
- Stem Cells (52)
- Transcranial Magnetic Stimulation (TMS) (44)
- Intermittent Hypoxia (38)
- Transcranial Direct Current Stimulation (tDCS) (32)
- Brain Machine Interface (BMI) (30)
- Neuromuscular Electrical Stimulation (NMES) (13)
Open and recruiting (9)
These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.
- Not yet recruitingNCT07799532
A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury
The goal of this clinical trial is to learn if NVG-291 can improve function in adults with chronic cervical motor-incomplete spinal cord injury. It will also learn about the safety of NVG-291.
18 US sites · Alabama, California, Colorado, Connecticut… - RecruitingNCT05553353
Dosing rTMS for Depression Post-SCI
Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population. Depression post-SCI impacts an individuals' quality of life and recovery.
1 US site · South Carolina - RecruitingNCT06989905
MEP Up-conditioning to Target Corticospinal Plasticity
Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist extensor).
1 US site · South Carolina - RecruitingNCT07179822
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections.
1 US site · South Carolina - RecruitingNCT05492188
Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure.
1 US site · South Carolina - RecruitingNCT05094362
Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning
The purpose of this study is to validate the capacity of a reflex training system to change the size of the targeted reflex. For this, the researchers are recruiting 25 individuals with chronic incomplete SCI who have spasticity in the leg to participate in the reflex training procedure.
2 US sites · South Carolina - RecruitingNCT02991690
Systemic Hypothermia in Acute Cervical Spinal Cord Injury
This study is a prospective multi-center trial designed to determine the safety profile and efficacy of modest (33ºC) intravascular hypothermia following acute cervical (C1 to C8) Spinal Cord Injury (SCI).
7 US sites · Arizona, Florida, Georgia, Indiana… - RecruitingNCT04263285
Treatment of Depression Post-SCI
Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective.
1 US site · South Carolina - RecruitingNCT05321017
Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle connections, and to examine the effects of training a brain-spinal cord-muscle response in individuals with incomplete spinal cord injury.
1 US site · South Carolina
Completed and closed (7)
Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.
- Completed NCT05530798 CEUS For Intraoperative Spinal Cord Injury
- Completed NCT01345019 Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
- Terminated NCT02660138 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
- Terminated NCT04815967 Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
- Completed NCT04286191 Physiological Changes Induced Through MEP Conditioning in People With SCI
- Completed NCT01243125 Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation
- Unknown NCT05959837 Usability of the Adapted Rower for People With Spinal Cord Injury
Where this list comes from
Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.
Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".