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SCI Clinical Trials in France

73 spinal cord injury clinical trials list a study site in France and none in the United States, and 15 are currently open to new participants. Each links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

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Open and recruiting (15)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT06538974

    Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population

    In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990.

    DevicesExoskeletonRehabilitationBladder FunctionBowel FunctionLeg MovementMental HealthMotor FunctionQuality of Life
    France
  • RecruitingNCT04496609

    Assessment of the Efficacy and Safety of EESS in Patients With Incomplete Spinal Cord Injuries

    Neurological disability caused by traumatic lesions of the spinal cord is a significant challenge for medicine and society. These lesions, leading to sublesional central nervous system dysfunction, include sensorimotor, vesico-sphincter and genito-sexual disorders.

    Electrical StimulationEpidural StimulationRehabilitationQuality of LifeSexual FunctionWalking Function
    France
  • Not yet recruitingNCT06794242

    Body Representation and Neuropathic Pain in Spinal Cord Injury

    Chronic pain is one of the main complications of spinal cord injury, has a very negative impact on quality of life, and persists over time despite the use of analgesic treatments.

    Pain Management
    France
  • RecruitingNCT06734000

    Cohorte COSCINUS - Biocollection

    COSCINUS is a standardized framework for evaluating temporal trends in SCI causes, SCI characteristics, and demographic patterns.

    Observational
    France
  • Not yet recruitingNCT06099340

    Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries.

    Neurological disorders \[such as Cerebral Vascular Accident (CVA) or Spinal Cord Injury (SCI)\] are among the most costly health problems to society in industrialized countries. For those affected, they generate severe restrictions in mobility, significantly altering their quality of life.

    RehabilitationMotor FunctionQuality of LifeSpasticityWalking Function
    France
  • RecruitingNCT04906928

    Evaluation of New MRI Sequences Including 3D-FGAPSIR for the Optimization of Inflammatory Spinal Cord Lesions Research

    * verification of inclusion and non-inclusion criteria * information and collection of consent * standard imaging protocol prescribed as part of the usual treatment: sagittal T1 and T2 slices after injection of contrast product (Gadolinium), 3D STIR and 3D PSIR sequence.

    DevicesDrugsObservational
    France
  • Not yet recruitingNCT07467382

    GOAT (Gait Observation of Achilles Tendon)

    The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis (post-stroke or incomplete spinal cord injury) compared to healthy…

    ObservationalSpasticityWalking Function
    France
  • RecruitingNCT07429188

    Impact Study on Users of Upper Limb Assistive Devices

    This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and Human and Social Sciences (HSS), targets the use case of employing…

    DevicesArm MovementHand Movement
    France
  • RecruitingNCT06920524

    Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)

    Botulinum toxin (BT) injections are a painful treatment frequently used to treat spasticity following central neurological damage (stroke, multiple sclerosis, spinal cord injury, head trauma). Tolerance of injections varies from patient to patient.

    DevicesRehabilitationMental HealthPain ManagementSpasticity
    France
  • RecruitingNCT07536386

    Self-balancing Personal Exoskeleton for SCI (WIP)

    This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

    Exoskeleton
    France
  • Not yet recruitingNCT06887309

    Spinal Cord Injury: Impact on Sensory, Motor, Behavioral and Cognitive Functions

    Spinal cord injury (SCI) causes a variety of sensory-motor deficits and neuropsychological consequences. Magnetic resonance imaging (MRI) reveals a reduction in the volume of the somato-sensory and motor cortices, as well as atrophy in the white matter bundles.

    Mental HealthQuality of Life
    France
  • Not yet recruitingNCT07656883

    Stereotactic Radiotherapy for SPinal Metastases With Limited Extent of Epidural Disease

    This study evaluates a new radiation treatment approach for patients with cancer that has spread to the spine (vertebral metastases) and involves limited extension around the spinal cord without causing compression (non-compressive epiduritis).

    Pain ManagementQuality of Life
    France
  • RecruitingNCT07334977

    Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation

    The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb…

    Transcranial Direct Current Stimulation (tDCS)Transcutaneous Stimulation
    France
  • Enrolling by invitationNCT06908850

    The Aim of This Research is to Better Understand How Complete Spinal Cord Injury May Change Erogenous Zones in Adult Males

    A complete spinal cord injury (SCI) in men is characterized by the total loss of motor skills and sensations below the injury. The loss of penile sensation, the erogenous zone primarily involved in sexual response, is involved in sexual dysfunction, impacting sexual pleasure and quality of life.

    Sexual Function
    France
  • RecruitingNCT05954845

    The Enteric Nervous System in Spinal Cord Injury: Study of the Enteric Nervous System and the Intestinal Epithelial Barrier Via Colonic Biopsies in Spinal Cord Injury Patients

    The goal of this clinical trial is to learn more about the enteric nervous system (ENS) and the intestinal epithelial barrier (IEB) in patients with spinal cord injury (SCI).

    France

Running, but closed to new participants (1)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT04189172

    MiDura-Study (Neuro-Patch in Duraplasty)

    The aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer

    ObservationalSurgical Procedure
    France, Germany

Completed and closed (57)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Unknown NCT04285970 Analysis of the Motion Activity Manual Wheelchair Users
  • Completed NCT07706517 Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
  • Unknown NCT05094752 Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Spinal Cord Injury
  • Completed NCT01935687 Clinical Evaluation of Instrumented Wheel as Biomedical Device Quantifying the Displacement Efficiency
  • Completed NCT00629642 Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis
  • Completed NCT02244931 Comparison of Three Different Assisting Devices to Power Manual Wheelchairs in Patients With Spinal Cord Injury
  • Terminated NCT03114345 Correlation Between Pressure Differences and Micro-vascularization Changes in Bedridden Paraplegic Patient
  • Terminated NCT02660359 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 2
  • Completed NCT01831414 Effect of Immersion Level on Respiratory Function of Spinal Cord Injury Patients During Balneotherapy
  • Withdrawn NCT04821635 Effects of FES-Rowing in Neurological Disorders (FES-ROW)
  • Completed NCT03482037 Effects of Rec 0/0438 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Injury
  • Terminated NCT01105260 Effects of an Early Wheelchair Reconditionong Program on Functional Independence in Spinal Cord-inured Individuals
  • Terminated NCT01023269 Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
  • Completed NCT04936217 Efficacy and Safety of a Continent Cutaneous Urinary Diversion in Spinal Cord Injury Patients
  • Completed NCT06421753 Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients
  • Terminated NCT03513783 Elbow Extension Restoration Surgery in People With Tetraplegia: Evolution of the Muscular Co-activations of the Upper Limb During the Post-operative Rehabilitation
  • Completed NCT04925882 Erector Spinae Plane Block in Lumbar Release Surgery
  • Completed NCT02506712 Evaluation of Physiological and Biomechanical Efficiency of the PAPAW
  • Completed NCT04110561 Evaluation of Safety and Performance of the Atalante System With Patients With Lower Limb Paralysis
  • Completed NCT06939634 Evaluation of Usability and Safety of the System Atalante in Patients With High Paraplegia and Tetraplegia
  • Completed NCT01953666 Evaluation of the Efficiency of Word Prediction Software to Text Input Speed for Tetraplegia
  • Completed NCT02144558 Fertility of Spinal Cord Injured Men
  • Unknown NCT03190863 Grasping Rehabilitation Using Motor Imagery With or With no Neurofeedback After Tetraplegia
  • Terminated NCT05403606 Guarantee Assessment in Skin Prevention Adapted to Real Life With a Connected Device After a Spinal Cord Injury.
  • Completed NCT06715631 Human Factors Validation Testing of the Wandercraft Personal Exoskeleton
  • Terminated NCT00476866 Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
  • Completed NCT00221767 Medico-economical Impact of the Brindley Neurosurgical Technique in France
  • Completed NCT03167801 Melatonin Secretion and Sleep Quality in Spinal Cord Injury Patients
  • Completed NCT02860403 Motor Imagery for Reach-to-grasp Rehabilitation After Tetraplegia
  • Completed NCT06474117 Muscle-tendon Interaction in the Spastic Sural Triceps During Gait
  • Completed NCT01357980 Neurogenic Detrusor Overactivity Following Spinal Cord Injury or Multiple Sclerosis
  • Completed NCT05391308 Overnight Upper Airway Infiltration in Spinal Cord Injury
  • Unknown NCT03434314 Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
  • Completed NCT04707144 Performance Evaluation of a 3D PSIR Sequence in MRI at 1.5T
  • Completed NCT04618978 Periodic Leg Movements' Diagnosis in Spinal Cord Injury: Actigraphy as an Alternative for Polysomnography?
  • Terminated NCT02974673 Pilot Study of Ejaculatory Dyssynergia by Electronic Microsensors of Sphincters
  • Completed NCT01834417 Preliminary Study Leading to Prevention of Pressure Ulcers by the Use of an On-board Device : Ergonomic Assessment of Wheelchair-seat Pressures in Spinal Cord Injured (SCI) Patients ( PRESDIE)
  • Terminated NCT02796235 Prospective and Monocentric Study of the Incidence of Venous Thromboembolic Disease (VTE) in Spinal Cord Injury (SCI) Patient Between 3 and 12 Months After SCI
  • Completed NCT04418050 Prosthetic Arthroplasties in Weight-bearing Shoulders
  • Completed NCT04402398 Psychometric Properties of a Mobile Application
  • Completed NCT02894437 Qualitative Study of Preventive Organization of the Pelvic Bedsores Injured Spinal Cord
  • Terminated NCT02412046 Quantification of the Pressure Threshold Related to Tissue Injury in Bedriden Paraplegics
  • Completed NCT06740006 Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
  • Unknown NCT02859792 Riluzole in the Treatment of Spasticity in the Traumatic Chronic Spinal Cord Injury Condition
  • Withdrawn NCT06347575 Safety and Tolerability of a Novel Implantable Neurostimulator for Ameliorate Erectile Function on Spinal Cord Injured Patients
  • Terminated NCT01606618 Self-esteem and Neuro-urological Follow-up in Patients With Spina Bifida or Spinal Cord Injury
  • Completed NCT02398331 Sexual Health of Spinal Cord Injured Females
  • Unknown NCT02833428 Spinal Cord and Artificial Intelligence
  • Completed NCT04300491 Study Examines the Feasibility, Safety and Benefits of Using a Specific Suspension Walking Device for Patients With Neurological Damage
  • Completed NCT07680361 Study of Home Use of the Jaco Robotic Manipulation Device by Individuals With Tetraplegia
  • Withdrawn NCT00213356 Study of the Nervous Control of the Anal Sphincter
  • Completed NCT01674764 Surgical Treatment for Spinal Cord Injury
  • Unknown NCT04412447 Training for Persons With Complete SCI for FES Cycling: a Case Series
  • Completed NCT02926391 UNiD 3D VBR Register
  • Completed NCT06608121 Upper Limb Muscle Strength Models for Patients With Motor Impairment.
  • Completed NCT02852317 Urinary Markers of Detrusor Overactivity in Spina Bifida Patients
  • Terminated NCT03721861 Use of Neural Functional Electrical Stimulation for the Recovery of Grasping Movements for Patient With Quadriplegia.

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".