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SCI Clinical Trials in Switzerland

115 spinal cord injury clinical trials list a study site in Switzerland and none in the United States, and 25 are currently open to new participants. Each links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

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Open and recruiting (25)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT06688916

    A Comprehensive Assessment of Altered Embodiment in Individuals With Spinal Cord Injury

    Spinal cord injury (SCI) occurs when trauma or other factors damage the spinal cord, disrupting the flow of sensory information from the body to the brain.

    Observational
    Switzerland
  • RecruitingNCT07234903

    ARC-IM Therapy To Support and Promote Recovery of Ambulatory Functions in People With Subacute and Chronic Spinal Cord Injury

    The EIGER study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to support and promote recovery of ambulatory functions, such as walking, in people with subacute and chronic spinal cord injury.

    Epidural StimulationWalking Function
    Switzerland
  • RecruitingNCT05665998

    Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation

    Cervical spinal cord stimulation can elicit arm and hand movements through recruitment of proprioceptive neurons in the dorsal roots. In participants with cervical spinal cord injury, the spare roots bellow the lesion can be used to reactivate motor function.

    Brain StimulationEpidural StimulationArm Movement
    Switzerland
  • RecruitingNCT03772548

    CNS Changes Following SCI

    The objective of this study is to better understand the structural and functional changes that the central nervous system (CNS) undergoes following spinal cord injury and how these changes relate to clinical measures.

    ObservationalPlasticity
    Switzerland
  • RecruitingNCT07456722

    Cardiac Morphology and Function in Individuals With Autonomic Dysreflexia

    This case-control study aims to investigate left ventricular remodeling in individuals with chronic spinal cord injury or disease (SCI/D) (≥10 years) and autonomic dysreflexia (AD) who have no prior cardiovascular history.

    ObservationalQuality of Life
    Switzerland
  • RecruitingNCT03053791

    Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait

    Spinal cord injuries are anatomically mostly incomplete, showing tissue bridges of the spinal cord at the injury site. Of the 60% functionally incomplete patients, about half face a life in the wheelchair. Besides conventional rehabilitation, no prominsing further treatment options exist.

    Brain StimulationWalking Function
    Switzerland
  • RecruitingNCT05187650

    Effectiveness of a Powered Exoskeleton Combined With FES for Patients With Chronic SCI: a RCT

    While there are a number of prospective studies evaluating powered exoskeletons in SCI patients, to date, not a single well-designed, randomized clinical trial has been published.

    ExoskeletonWalking Function
    Switzerland
  • RecruitingNCT05111093

    Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury

    The HemON study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to improve hemodynamic management and trunk control in people with sub-acute or chronic spinal cord injury (\>= 1 month post injury) between C3 and T6 inclusive, who suffer from…

    Epidural StimulationBlood Pressure
    Switzerland
  • RecruitingNCT01571531

    European Multicentre Study of Human Spinal Cord Injury

    Today there is accumulating evidence from animal experiments that regeneration can be induced after a spinal cord injury (SCI). Consequently in the near future, new therapeutic approaches to induce some regeneration will be included in the treatment of patients with SCI.

    Safety
    Switzerland
  • RecruitingNCT05681936

    Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury

    Building on recent improvements, state-of-the-art functional MRI will be applied as an advanced diagnostic tool for the lumbosacral cord in spinal cord injury (SCI) patients to characterize the remaining neuronal activity of the motor and sensory neurons.

    ObservationalBladder FunctionHand MovementMotor FunctionPain ManagementQuality of LifeRegeneration
    Switzerland
  • RecruitingNCT03621254

    Investigation Into Optimal FES Training Characteristics After Spinal Cord Injury

    The aim of this study is to investigate two different modalities of functional electrical stimulation (FES) leg exercise in patients with spinal cord injury (SCI). The primary outcomes being compared are 1. FES-induced leg aerobic fitness, and 2. FES-induced leg strength.

    RehabilitationBreathing Function
    Switzerland
  • RecruitingNCT06817577

    NG004 in Spinal Cord Injury Patients

    This is the FIH, multicenter, open-label, sequential, multiple ascending dose trial of NG004 in patients with acute incomplete cervical SCI. The trial will evaluate the safety, tolerability, and PK of 4 dose regimens of NG004, and will evaluate the maximum tolerated dose of NG004.

    Rehabilitation
    Germany, Switzerland
  • RecruitingNCT06443281

    Pain Phenotyping in Patients With Neuropathic Pain After Spinal Cord Injury

    The development of neuropathic pain is one of the most debilitating sequels after a spinal cord injury (SCI). The overall aim of this study is to investigate potential underlying pathophysiological mechanisms of neuropathic pain after SCI.

    Pain Management
    Switzerland
  • RecruitingNCT04967274

    Reticulospinal Control of Movements

    Accurate movement execution is a result of a complex interplay between various muscle groups whose activity is controlled by different areas of the central nervous system.

    RehabilitationHand Movement
    Switzerland
  • RecruitingNCT06775925

    Robot-assisted vs. Conventional Occupational Therapy of the Upper Limb in Individuals With Cervical Spinal Cord Injury

    The goal of this clinical trial is to learn the effects of robot-assisted therapy using the ArmeoSpring on upper limb function compared to conventional occupational therpay in individuals with cervical spinal cord injury (cSCI).

    RehabilitationArm MovementHand Movement
    Switzerland
  • RecruitingNCT07461259

    Safety and Feasibility of TWIICE Rise - Phase 2

    The aim of this study is to assess the safety and the feasibility of two versions of TWIICE Rise for exoskeleton-assisted ambulation in patients with a spinal cord injury.

    ExoskeletonWalking Function
    Switzerland
  • RecruitingNCT07245706

    Shoulder Health After Rehabilitation and Performance Training

    The goal of this study is to investigate the impact of a home-based shoulder strength training on the overall shoulder health in manual wheelchair users, and if the timepoint of such a training makes a difference.

    DevicesQuality of Life
    Switzerland
  • RecruitingNCT06845904

    Study on Preliminary Safety and Efficacy of Epidural Electrical Stimulation to Manage Lower Urinary Tract Dysfunction After Spinal Cord Injury

    This clinical trial aims to assess the preliminary safety and efficacy of Epidural Electrical Stimulation (EES) therapy in managing lower urinary tract dysfunction in individuals with sub-acute or chronic spinal cord injury (SCI).

    Epidural StimulationBladder Function
    Switzerland
  • RecruitingNCT05942339

    Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury (BoxSwitch)

    The purpose of this pre-market clinical study is to assess the preliminary safety and efficacy of the ARC Therapy using the ARC-IM Lumbar System at supporting mobility in participants who have previously received a spinal array and an implantable pulse generator (IPG) either through the STIMO…

    Epidural StimulationLeg MovementQuality of Life
    Switzerland
  • RecruitingNCT06870331

    The Effect of Probiotic and Prebiotic Supplementation on Gastrointestinal Health in Individuals With Chronic Spinal Cord Injury

    The goal of this clinical trial is to evaluate the effect of probiotic and prebiotic supplementation in individuals with chronic spinal cord injury experiencing gastrointestinal complaints.

    Nutrition
    Switzerland
  • Not yet recruitingNCT06905470

    The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation

    The goal of this clinical trial is to assess the effects of eccentric arm-crank (KREHA) training compared to standard clinical routine strength (STAN) training in individuals undergoing primary spinal cord injury (SCI) rehabilitation.

    RehabilitationArm Movement
    Switzerland
  • RecruitingNCT03965299

    Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord Injury

    Most patients with spinal cord injury (SCI) develop neurogenic lower urinary tract dysfunction (NLUTD), one of the most devastating sequelae of SCI which ultimately can lead to renal failure. We urgently need an intervention that prevents NLUTD before irreversible damage occurs.

    Transcutaneous StimulationBladder Function
    Switzerland
  • RecruitingNCT06892080

    Urine Incontinence Occurrence and Sexual Hormones in Women With Chronic Spinal Cord Injury/Disease - a Pilot Study

    There is a knowledge gap about the influence of the menstrual cycle on bladder function in women with spinal cord injury. So far, studies regarding urinary incontinence have primarily focused on women after menopause.

    Bladder FunctionSexual Function
    Switzerland
  • Not yet recruitingNCT07745686

    VALSE: Integration of Neuromodulation and Exoskeleton Systems for Mobility in Individuals With Chronic Spinal Cord Injury

    The purpose of this clinical study is to evaluate the preliminary safety and feasibility of using the VALSE system, which combines spinal cord stimulation with the TWIICE robotic exoskeleton, to support motor recovery and reduce reliance on laboratory-based equipment during rehabilitation in…

    Brain Machine Interface (BMI)DevicesElectrical StimulationEpidural StimulationExoskeletonRehabilitationSafetyMotor FunctionWalking Function
    Switzerland
  • RecruitingNCT07165353

    Virtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI

    About 70% of people with a spinal cord injury in Switzerland have chronic pain that lasts more than 3 to 6 months. This pain can be caused by muscle or joint problems, or by nerve damage (neuropathic pain).

    Pain Management
    Switzerland

Running, but closed to new participants (4)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT06243952

    Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb Rehabilitation

    The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with lumbar targeted epidural electrical stimulation (EES) of the spinal cord to restore voluntary motor functions of lower limbs in participants with…

    Epidural StimulationWalking Function
    Switzerland
  • Active, not recruitingNCT04632290

    Brain-controlled Spinal Cord Stimulation in Patients With Spinal Cord Injury

    In a current first-in-human study, called Stimulation Movement Overground (STIMO, NCT02936453), Epidural Electrical Stimulation (EES) of the spinal cord is applied to enable individuals with chronic severe spinal cord injury (SCI) to complete intensive locomotor neurorehabilitation training.

    Epidural StimulationWalking Function
    Switzerland
  • Active, not recruitingNCT05976087

    Improving Grasp Function in People With Sensorimotor Impairments by Combining Electrical Stimulation With a Robotic Hand Orthosis

    Hand motor and sensory impairments resulting from neurological disorders or injuries affect more than 50 million individuals worldwide.

    Hand Movement
    Switzerland
  • Active, not recruitingNCT07739134

    Multimodal Tracking of Therapy Activity and Effort During Rehabilitation

    This study looks at whether everyday rehabilitation therapy sessions can be recorded and measured in a more complete, objective way. Today, therapists usually document sessions by hand, and the notes can vary a lot from one therapist to another.

    ObservationalRehabilitationBreathing Function
    Switzerland

Completed and closed (86)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Withdrawn NCT02970773 Absorption of Rivaroxaban in Patients With Cervical Spinal Cord Injury
  • Completed NCT04052776 Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES
  • Completed NCT00406016 Acute Safety, Tolerability, Feasibility and Pharmacokinetics of Intrath. Administered ATI355 in Patients With Acute SCI
  • Completed NCT02098135 ArmeoSenso - Home Therapy and Assessment for Patients With Arm Impairments Based on Wearable Movement Sensors
  • Completed NCT02138344 Assessment of Neuropathic Pain
  • Completed NCT03886610 Association of Quantitative and Functional Imaging With Clinical Outcome After Spinal Cord Injury
  • Completed NCT03534518 Body Weight Supported Training Study
  • Completed NCT01853488 Bone Strength After Spinal Cord Injury
  • Completed NCT05098587 Brain Activity Patterns in Persons With Spinal Cord Injury and Neuropathic Pain After a Virtual Walking Training Program
  • Completed NCT01208584 Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions
  • Terminated NCT03815721 Carry-over Effects of Repetitively Applied Transcutaneous Spinal Cord Stimulation on Spasticity
  • Unknown NCT01470950 Characterization of the Changes in the Signalling Pathways During Spinal Cord Injury-induced Skeletal Muscle Atrophy
  • Completed NCT01477502 Clinical Value of Homeopathic Prophylaxis of Recurrent Urinary Tract Infections in Persons With Spinal Cord Injury
  • Unknown NCT04965727 Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Injury
  • Completed NCT04292717 Deficit-specific Training in Spinal Disorders
  • Completed NCT02268266 ERIGO® Life- Control of Cardiovascular Parameters Via Verticalization and Simultaneous Mobilization
  • Completed NCT02265042 Effect of Electrostimulation on Denervated Muscles in Individuals With Spinal Cord Injury
  • Completed NCT01147185 Effectiveness of Automated Locomotor Training in Patients With Acute Incomplete Spinal Cord Injury: A Multicenter Trial
  • Completed NCT01600404 Effects of Antimuscarinics on Cognition in Spinal Cord Injury
  • Completed NCT06200493 Effects of Maximum Strength and Acceleration Ability on Performance and Training in Wheelchair Sports
  • Completed NCT03137108 Effects of Transcutaneous Spinal Cord Stimulation on Residual Voluntary Motor Control in Individuals With Incomplete Spinal Cord Injury
  • Terminated NCT02080039 Electrical Stimulation of Denervated Muscles After Spinal Cord Injury
  • Completed NCT03898258 Evaluation of the German Short-Form Qualiveen Questionnaire
  • Completed NCT02203994 Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury
  • Completed NCT03153033 Fatigue Induced by Overground Wheelchair Propulsion in Persons With a Spinal Cord Injury: Upper Limb Saving or Straining?
  • Completed NCT03908047 Functional Changes in the Brain After Tibial Nerve Stimulation: a Pilot Study
  • Terminated NCT03048331 Functional Electrical Stimulation (FES) and Reconstructive Tetraplegia Hand and Arm Surgery
  • Completed NCT03343132 Gait Adaptability: Tracking Locomotor Recovery After Incomplete Spinal Cord Injury
  • Unknown NCT02808078 Gait Adaptation for Stroke Patients With Augmented Reality
  • Completed NCT03069404 INSTrUCT-SCI: INdependent Observational STUdy of Cell Transplantation in SCI
  • Completed NCT04049994 Immunomodulation Therapy for Urinary Tract Infections
  • Completed NCT03004144 Impact of Assistive Forces on Activities of Daily Living
  • Completed NCT01297647 Incidence of Urinary Tract Infection After Urodynamic Investigation
  • Completed NCT02083328 Influence of Caffeine on HRV and Exercise Performance in Spinal Cord Injury
  • Completed NCT02891096 Inspiratory Strength and Respiratory Complications After SCI Injury
  • Withdrawn NCT04008160 Intelligent Underwear (IU) in Paraplegics
  • Completed NCT02149186 Interactive Motor Imagery in Virtual Reality
  • Completed NCT02150629 Investigating Kinematic and Electromyographic Changes After SCI and Their Relation to Clinical and Functional Outcome
  • Completed NCT02138149 Is the Nerve Growth Factor (NGF) a Useful Biomarker in Neurogenic Bladder Dysfunction After Spinal Cord Injury?
  • Completed NCT03458169 LEAP a New Overground Body Weight Support Robot: Usability Trial
  • Unknown NCT04052009 Locomotor Training in Individuals With Incomplete Spinal Cord Injury. A Pilot Study
  • Completed NCT01087918 Lokomat Versus Strength Training in Chronic Incomplete Spinal Cord Injury
  • Terminated NCT01725880 Long-Term Follow-Up of Transplanted Human Central Nervous System Stem Cells (HuCNS-SC) in Spinal Cord Trauma Subjects
  • Completed NCT02149511 Longitudinal Morphometric Changes Following SCI
  • Completed NCT01943201 Low Friction Bed Sheet
  • Completed NCT04032314 Lower Extremity Outcome Measures in SCI
  • Completed NCT06309888 Magnetic Resonance Imaging of Cognitive Deficits in the Brain of Individuals With Spinal Cord Injury
  • Completed NCT03935321 NISCI - Nogo Inhibition in Spinal Cord Injury
  • Completed NCT01297660 Neuro-urological Outcome After Spinal Cord Injury
  • Terminated NCT02538809 Novel mRNA-based Urine Test for Bladder Cancer in Spinal Cord Injury Individuals
  • Unknown NCT03434314 Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
  • Completed NCT02132702 Performance Attributes and User Progression While Using Ekso
  • Completed NCT02148887 Plasticity of Grey and White Matter in Response to Motor Skill Training in Healthy Individuals and Those With Spinal Cord Injury
  • Completed NCT02459028 Positive Psychology Interventions in Individuals With Chronic Pain and Spinal Cord Injury
  • Completed NCT01980784 Posttraumatic Changes in Energy Expenditure and Body Composition in Patients With Acute Spinal Cord Injury
  • Completed NCT01891110 Prevention of Orthostatic Hypotension With Electric Stimulation in Persons With Acute SCI
  • Completed NCT04659408 Probiotic and Prebiotic Supplementation in Elite Athletes with Spinal Cord Injury
  • Completed NCT03707704 Quality Control of a Strengthening Protocol in Subjects With Spinal Cord Injury
  • Completed NCT01297673 Reflux in Spinal Cord Injury Patients With Neurogenic Lower Urinary Tract Dysfunction
  • Completed NCT02138201 Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI - a Pilot Study
  • Terminated NCT04994886 Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury
  • Completed NCT01601041 Role of Residual Urine and Asymptomatic Prostatitis in the Development of Urinary Tract Infections in Spinal Cord Injury
  • Completed NCT02936453 STIMO: Epidural Electrical Simulation (EES) With Robot-assisted Rehabilitation in Patients With Spinal Cord Injury.
  • Terminated NCT01598103 Safety and Efficacy of SAF312 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Lesions
  • Unknown NCT05926310 Safety and Feasibility of TWIICE Rise
  • Unknown NCT04071938 Shared Responsibility Between General Practitioners and Highly Specialized Hospitals in Spinal Cord Injury
  • Withdrawn NCT02449512 Somatosensory Evoked Potentials From the Lower Urinary Tract
  • Completed NCT04241666 Sonographic Examination of Renal Function in Individuals With Long-term Spinal Cord Injury
  • Completed NCT01299792 Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction
  • Completed NCT05777941 Strength Training With Eccentric Arm-cranking in Para-athletes
  • Completed NCT01321333 Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury
  • Withdrawn NCT04196114 Study on Feasibility of Stimulation on the Lumbar Part of the Spinal Cord to Improve Mobility Recovery in Patients With Sub-acute Spinal Cord Injury
  • Completed NCT01768910 Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction
  • Completed NCT04914975 The Effect of NMES on Bowel Management in People With Chronic SCI
  • Completed NCT04904770 Time Performance of Scoop Stretcher Versus Vacuum Mattress for Prehospital Spinal Stabilization
  • Withdrawn NCT01043848 Treatment of Neurogenic Detrusor Overactivity: Early Versus Late Pudendal Nerve Stimulation in Spinal Cord Injury (SCI) Patients
  • Completed NCT02098122 Upper Limb Activity in Human SCI Rehabilitation
  • Completed NCT06710808 VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
  • Terminated NCT02720341 VIT-ARMin Virtual, Intensified and Patient-tailored Robotic Arm Therapy With the Exoskeleton Robot ARMin
  • Completed NCT05022095 Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language
  • Completed NCT02425332 Validation of a Novel Robot-aided Assessment of Gait Ability
  • Completed NCT06256159 Validity and Reliability of the 12-item Multiple Sclerosis Walking Scale (12-WS) in Subjects With Spinal Cord Injury
  • Completed NCT04555759 Validity and Reliability of the 2-minute Walk Test in Individuals With a Spinal Cord Injury
  • Completed NCT04652544 Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury
  • Completed NCT02621320 Vitamin D Supplementation in Wheelchair Indoor Athletes
  • Completed NCT02550834 Wheelchair Indoors Curling With SCI patients_RCT

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".