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SCI Clinical Trials in United Kingdom

70 spinal cord injury clinical trials list a study site in United Kingdom and none in the United States, and 12 are currently open to new participants. Each links to its full ClinicalTrials.gov record for eligibility, contacts and exact locations. Last refreshed 2026-09-12.

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This is research, not treatment. A clinical trial is a study. It may involve a placebo, carries unknown risks, and is not a substitute for proven care. Be wary of any "trial" that charges you to take part. Talk with your SCI doctor before enrolling, and read the full eligibility and risks on ClinicalTrials.gov. Not medical advice.

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Open and recruiting (12)

These trials are recruiting, about to recruit, or enrolling by invitation. Status comes straight from ClinicalTrials.gov and can change without notice.

  • RecruitingNCT05615766

    Assessment of a Robotic Exoskeleton for Upper Limb Rehabilitation

    Rehabilitation robotics has the potential to facilitate rehabilitation at home and empower people with spinal injuries to self-manage increasing their independence and improving their quality of life.

    ExoskeletonRehabilitationArm MovementHand Movement
    United Kingdom
  • Not yet recruitingNCT07015099

    Complications Associated With Delayed Admission to Spinal Injury Unit

    The aim of this study is to determine the prevalence of complications including PUs at time of admission to a regional spinal injury rehabilitation unit (MCSI), the relationship between wait time to admission for specialist SCI rehabilitation and complication n occurrence, neurological recovery,…

    ObservationalRehabilitation
    United Kingdom
  • RecruitingNCT04936620

    Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling

    QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.

    Safety
    Austria, Belgium, China, Czechia…
  • RecruitingNCT07705256

    EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation

    This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury. In the main study, participants will use a virtual-reality feedback system that is controlled by surface electromyography (EMG).

    Electrical StimulationFunctional Electrical Stimulation (FES)RehabilitationTranscranial Magnetic Stimulation (TMS)Arm MovementHand MovementMental HealthPain ManagementQuality of Life
    United Kingdom
  • RecruitingNCT07127172

    GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

    The GB-PRIME Study is an early feasibility study designed to assess the clinical safety and functionality of the Neuralink N1 Implant and R1 Robot. This study involves participants who have tetraparesis, tetraplegia, or a diagnosis that may lead to these conditions.

    Brain Stimulation
    United Kingdom
  • RecruitingNCT06244160

    High Flow Oxygen Therapy After Spinal Cord Injury

    The goal of this feasibility study is to learn about the ability to use a different form of oxygen therapy (known as high flow oxygen therapy) in patients who have a spinal cord injury in the upper back or neck. The main questions it aims to answer are: 1.

    Rehabilitation
    United Kingdom
  • RecruitingNCT06515223

    Improving Pelvic Rehabilitation Using Epidural Stimulation After Spinal Cord Injury

    The investigators will recruit up to 20 volunteers with chronic, supra-sacral SCI. Following screening, eligible participants will enter 'Phase I', they will complete baseline outcome measures and then have the epidural spinal cord stimulator (eSCS) implanted with either percutaneous or paddle…

    Epidural StimulationBladder Function
    United Kingdom
  • RecruitingNCT07303582

    Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities

    Spasticity is an umbrella term for impairments of muscle tone and control in people with damage to the brain and spinal cord. It is highly prevalent and results in pain, stiffness, and contribute to difficulties in activities of daily living.

    Pain ManagementSpasticity
    United Kingdom
  • RecruitingNCT07099911

    Neuromuscular Electrical Stimulation and Glucose Control in Spinal Cord Injury

    Overall aim: To identify the impact and acceptability of a novel method of neuromuscular electrical stimulation (NMES) for improving glucose control using a dual stable isotope tracer OGTT in individuals with spinal cord injury (SCI). Objective 1: 1.

    Electrical StimulationNutrition
    United Kingdom
  • RecruitingNCT06965101

    To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway

    The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the need for a planning CT (pCT) scan prior to treatment.

    Quality of Life
    United Kingdom
  • RecruitingNCT05991804

    Upper Limb Spinal Cord Stimulation for Rehabilitation Enhancement

    In the United Kingdom, there are more than 1000 new cases of spinal cord injury (SCI) each year, with around half of these injuries affecting the cervical spine.

    Transcutaneous StimulationArm MovementHand Movement
    United Kingdom
  • Not yet recruitingNCT07208188

    tESCS for Upper Limb Rehab in Spinal Cord Injury

    Regaining hand and arm function is an important step towards regaining independence following high-level spinal cord injury (tetraplegia).

    Transcutaneous StimulationArm MovementHand Movement
    United Kingdom

Running, but closed to new participants (1)

Active studies that are no longer enrolling. Useful for seeing where the field is heading.

  • Active, not recruitingNCT06957483

    Pilot Study of a Sedentary Behaviour Intervention for Individuals With a Spinal Cord Injury

    Individuals with spinal cord injury have a greater risk of heart disease and stroke than non-disabled individuals. This might be partly because wheelchair users engage in high amounts of sedentary behaviour.

    Rehabilitation
    United Kingdom

Completed and closed (57)

Completed, terminated, withdrawn, or last reported with an unknown status. Completed trials are where published results come from.

  • Completed NCT01606202 A Study of Cannabis Based Medicine Extracts and Placebo in Patients With Pain Due to Spinal Cord Injury
  • Completed NCT02200393 Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia
  • Unknown NCT01800409 Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation
  • Unknown NCT00202631 Abdominal Functional Electrical Stimulation in Tetraplegia
  • Completed NCT06583538 An Online Rehabilitation Programme for People with SCI
  • Completed NCT01852279 BCI and FES for Hand Therapy in Spinal Cord Injury
  • Completed NCT03307954 Bone Mineral Density Ekso Therapy Study
  • Completed NCT02678494 Brain-Train Home Based Pain Treatment
  • Unknown NCT05084170 Cingulotomy for Refractory Neuropathic Pain Following Spinal Cord Injury (CRNP-SCI)
  • Completed NCT00629642 Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis
  • Unknown NCT02870426 Collection and Characterisation of Human Olfactory Ensheathing Cells
  • Unknown NCT00204113 Control of Unsupported Paraplegic Standing
  • Terminated NCT03254862 Different Stimulation Patterns to Reduce Muscle Fatigue During FES
  • Unknown NCT05502614 Dorsal Genital Nerve Stimulation for Bladder Management After SCI
  • Terminated NCT02660359 Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 2
  • Unknown NCT04665492 EEG Predictors of Neuropathic Pain in SCI
  • Completed NCT03611803 EFFECTS OF ROBOTIC TRAINING ON VASCULAR HEALTH OF INDIVIDUALS WITH SCI
  • Unknown NCT02334410 Early Intervention to Reduce Bone Loss After Spinal Cord Injury
  • Terminated NCT01023269 Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
  • Completed NCT04307303 Electrical Stimulation of Abdominal Muscles for Bowel Management in People With Spinal Cord Injury
  • Unknown NCT00204126 Exercise Testing During Treadmill Gait in Incomplete Spinal Cord Injury
  • Unknown NCT01943669 Exoskeletons for Spinal Cord Injury: A Feasibility Study
  • Unknown NCT01943656 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study
  • Completed NCT07385456 FES Arm Cycling on Functional Ability and Strength in People With SCI
  • Unknown NCT04064385 Functional Electrical Stimulation Cycling in SCI
  • Completed NCT04011137 High-intensity Interval Training and Mixed Meal Responses in Persons With Spinal Cord Injury
  • Unknown NCT04397250 High-intensity Interval Training for Cardiometabolic Health in Persons With Spinal Cord Injury
  • Unknown NCT02721615 Injured Spinal Cord Pressure Evaluation
  • Completed NCT03661294 Investigating the Energy Expenditure of Acute Spinal Cord Injured Patients
  • Completed NCT05777499 MUSic Therapy In Complex Specialist Neurorehabilitation
  • Terminated NCT04367623 Motor Conditioning to Enhance the Effect of Physical Therapy
  • Unknown NCT06075056 Neuro-navigated TMS for Chronic SCI Patients
  • Completed NCT02178917 Neurofeedback for Treatment of Central Neuropathic Pain (CNP) in Sub-acute Spinal Cord Injury (SCI)
  • Unknown NCT04849676 Neurofeedback to Improve Spasticity After Incomplete Spinal Cord Injury
  • Completed NCT07810712 PNS Motor Stimulation Study
  • Unknown NCT03434314 Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
  • Unknown NCT00204100 Paraplegic Cycling: Improving Health After Spinal Cord Injury
  • Completed NCT03257982 Patient Self-managed BCI-FES
  • Completed NCT02591901 Preventing UTIs in Chronic Neurogenic Bladder Dysfunction (Mix Methods)
  • Terminated NCT04265560 Progressive Resistance Training in Acute Spinal Cord Injury
  • Completed NCT05249985 Protein Supplementation and Neuromuscular Electrical Stimulation in Persons With SCI
  • Unknown NCT04015362 Pulsed Magnetic Stimulation - Managing Spasticity in Spinal Cord Injury
  • Completed NCT00727584 Radiation Therapy in Treating Patients With Metastatic Spinal Cord Compression
  • Completed NCT04102826 Restoration of Arm Function in People With High-level Tetraplegia
  • Withdrawn NCT05968352 Restoration of Bladder Function in Spinal Cord Injury
  • Completed NCT02417532 Safety and Feasibility Evaluation of Robot Assisted Physiotherapy Exercises With REX
  • Terminated NCT03536338 Spinal Stimulation Sit-to-Stand Training After Spinal Cord Injury
  • Completed NCT04132596 Spinal Stimulation in Chronic Spinal Cord Injury
  • Completed NCT01674764 Surgical Treatment for Spinal Cord Injury
  • Completed NCT05801536 TCES for Upper Limb Function in Cervical SCI
  • Completed NCT04964635 TETRAGRIP II - Usability Trial of an FES Orthosis for People With Tetraplegia.
  • Unknown NCT06296771 The Effect of a Combined Aerobic and Resistance Exercise (CARE) Training Programme on Cardiometabolic Outcomes in Individuals With Chronic Spinal Cord Injury: A Randomised Controlled Trial
  • Completed NCT02914418 Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study
  • Completed NCT05504200 Transcutaneous Spinal Cord Stimulation With Bladder and Pelvic Floor Muscle Training
  • Completed NCT06618404 UK Prevalence of Mental Health After SCI
  • Completed NCT06154122 Virtual Reality Upper Limb Therapy for People With Spinal Cord Injury
  • Unknown NCT04902482 iCycle II: Recovery of Function Through FES Cycling With VR Biofeedback in People With SCI.

Where this list comes from

Trials are pulled daily from the ClinicalTrials.gov registry and tagged by what they study and what they target. This page reflects the 2026-09-12 refresh of the 2,167 spinal cord injury trials SCI.help tracks. Eligibility criteria, study contacts, exact sites, and results live on each trial's ClinicalTrials.gov record, linked above. The full dataset is public at /data/sci_trials.min.json.

Before contacting a study team, read clinical trials and SCI research, honestly and how to spot a predatory "trial".